Results 1 to 10 of about 10,438 (226)

Multicomponent Therapeutics of Berberine Alkaloids [PDF]

Evidence-Based Complementary and Alternative Medicine, 2013
Although berberine alkaloids (BAs) are reported to be with broad-spectrum antibacterial and antiviral activities, the interactions among BAs have not been elucidated. In the present study, methicillin-resistantStaphylococcus aureus(MRSA) was chosen as a model organism, and modified broth microdilution was applied for the determination of the ...
Luo, Jiaoyang, Yan, Dan, Yang, Meihua, Dong, Xiaoping, Xiao, Xiaohe   +4 more
openaire   +3 more sources

Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review [PDF]

, 2020
Background A growing number of epidemiological studies indicate that metabolic syndrome (MetS) and its associated features play a key role in the development of certain degenerative brain disorders, including Alzheimer’s disease and vascular dementia ...
Bell, J.D., Bell, J.D., Bligh, S.W.A., Bligh, S.W.A., Katsuno, T., Katsuno, T., Parkinson, J., Parkinson, J., Shinjyo, N., Shinjyo, N.   +9 more
core   +1 more source

Comparison of chemical profiles and effectiveness between Erxian decoction and mixtures of decoctions of its individual herbs : a novel approach for identification of the standard chemicals [PDF]

, 2017
Acknowledgements This study was partially supported by grants from the Seed Funding Programme for Basic Research (Project Number 201211159146 and 201411159213), the University of Hong Kong.
Cheung, H. P., Chung, F. W. S., Lao, L. X., Ng, T. B., Sze, S. C. W., Tong, Y., Wang, S. W., Zhang, Y. B., Zhang, Z. J.   +8 more
core   +4 more sources

Antidiabetic and antimicrobial activities of fractions and compounds isolated from Berberis brevissima Jafri and Berberis parkeriana Schneid [PDF]

, 2013
Methanol extracts of the roots of B. brevissima and B. parkeriana were examined for antidiabetic and antimicrobial activities. Six compounds i.e berberine, 8-oxo-berberine, dehydrocheilanthifoline, columbamine, jatrorrhizine and glutamic acid were ...
Ali, Saqib, Almazeb, Muhammad, Clements, Carol, Ferro, Valerie, Gray, Alexander, Igoli, John, Khan, M Rafiullah, Rashid, Mamoon-Ur, Semaan, Dima, Shah, Syed Qaisar   +9 more
core   +1 more source

Alternative final steps in berberine biosynthesis in Coptis japonica cell cultures [PDF]

, 1988
In Coptis japonica cell cultures an alternative pathway has been discovered which leads from (S)-tetrahydrocolumbamine via (S)-canadine to berberine. The two enzymes involved have been partially purified.
Galneder, E., Rüffer, Martina, Tabata, M., Wanner, G., Zenk, Meinhart H.   +4 more
core   +1 more source

Canadine synthase from Thalictrum tuberosum cell cultures catalyses the formation of the methylenedioxy bridge in berberine synthesis [PDF]

, 1994
An enzyme system catalysing the formation of the methylenedioxy bridge at ring A of (S)-canadine [ = (S)-tetrahydroberberine] from (S)-tetrahydrocolumbamine has been detected in microsomal preparations from different Ranunculaceae and Berberidaceae cell ...
Rüffer, Martina, Zenk, Meinhart H.
core   +2 more sources

Anticancer Potential of Natural Isoquinoline Alkaloid Berberine

Journal of Exploratory Research in Pharmacology, 2021
Despite the availability of several therapeutic strategies and many drugs, the ability to cure most cancers remains a challenge. Natural products have been used for the treatment of numerous diseases, including cancer. The present review delineates various preclinical studies performed in vitro and in vivo that explore the anticancer potential of ...
openaire   +1 more source

Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum [PDF]

, 2014
Alkaloids play a key role in higher plant defense against pathogens and herbivores. Following its biosynthesis in root tissues, nicotine, the major alkaloid of Nicotiana species, is translocated via xylem transport toward the accumulation sites, leaf ...
Goossens, Alain, Hayashida, Minaho, Ito, Shingo, Minami, Shota, Morita, Masahiko, Moriyama, Yoshinori, Moriyasu, Masataka, Omote, Hiroshi, Shitan, Nobukazu, Sugiyama, Akifumi, Takanashi, Kojiro, Yazaki, Kazufumi   +11 more
core   +4 more sources

The formation of corydaline and related alkaloids in Corydalis cava in vivo and in vitro [PDF]

, 1994
Kein ...
Bauer, Wolfgang, Rüffer, Martina, Zenk, Meinhart H.   +2 more
core   +1 more source

Structure-activity relationships of synthetic analogs of jasmonic acid and coronatine on induction of benzo[c]phenanthridine alkaloid accumulation in Eschscholzia californica cell cultures [PDF]

, 2000
A facile test system based on the accumulation of benzo[c]phenanthridine alkaloids in Eschscholzia californica cell suspension culture (an indicator of defense gene activation) has been used to analyze a series of synthetic compounds for elicitor-like ...
Dzink J.L., Holbrook L., Kutchan T.M., Quinkert G., Rosco A., Yamane H.   +5 more
core   +1 more source