Results 21 to 30 of about 81,348 (224)

Fungicidal and Herbicidal Activities of Berberine Related Alkaloids

Bioscience, Biotechnology, and Biochemistry, 2000
The 23 quaternary and tertiary protoberberines related to berberine were tested for in vitro and/or in vivo fungicidal and herbicidal activities. Among the compounds tested, there was some activity observed with some of only the protoberberinium salts, but not sufficiently strong or broad spectrum for agrochemical use. From the structure-activity point
IWASA, Kinuko, MORIYASU, Masataka, NADER, Bassam   +2 more
openaire   +2 more sources

Berberine and palmatine inhibit the growth of human rhabdomyosarcoma cells [PDF]

, 2019
Published online: 29 Aug 2019A natural isoquinoline alkaloid, berberine, has been known to exhibit anti-tumor activity in various cancer cells via inducing cell cycle arrest. However, it has not been investigated whether berberine and its analogs inhibit
Nakamura, Shunichi, Shinji, Sayaka, Umezawa, Koji, Takaya, Tomohide, Nihashi, Yuma   +4 more
core   +1 more source

Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus

Frontiers in Aging Neuroscience, 2023
There is a close relationship between Alzheimer's disease (AD) and diabetes mellitus (DM), and the link between the two is often referred to as type 3 diabetes mellitus (T3DM).
Juan Huang, Juan Huang, Juan Huang, Nanqu Huang, Qianhua Mao, Jingshan Shi, Yu Qiu   +6 more
doaj   +1 more source

Berberine, an Epiphany Against Cancer

Molecules, 2014
Alkaloids are used in traditional medicine for the treatment of many diseases. These compounds are synthesized in plants as secondary metabolites and have multiple effects on cellular metabolism.
Luis Miguel Guamán Ortiz, Paolo Lombardi, Micol Tillhon, Anna Ivana Scovassi   +3 more
doaj   +1 more source

Modulatory Effect of Chelidonium majus Extract and Its Alkaloids on LPS-Stimulated Cytokine Secretion in Human Neutrophils

Molecules, 2020
Due to certain differences in terms of molecular structure, isoquinoline alkaloids from Chelidonium majus engage in various biological activities.
Sylwia Zielińska, Monika Ewa Czerwińska, Magdalena Dziągwa-Becker, Andrzej Dryś, Mariusz Kucharski, Anna Jezierska-Domaradzka, Bartosz J. Płachno, Adam Matkowski   +7 more
doaj   +1 more source

Anti-protozoal activity of aporphine and protoberberine alkaloids from Annickia kummeriae (Engl. & Diels) Setten & Maas (Annonaceae) [PDF]

, 2013
BACKGROUND: Malaria, trypanosomiasis and leishmaniasis have an overwhelming impact in the poorest countries in the world due to their prevalence, virulence and drug resistance ability.
Swaleh, S. M., Hassanali, Ahmed, Ndiege, Isaiah O, Brun, R., Dalsgaard, Petur, Ahmed Hassanali, Ndiege, I. O., Malebo, Hamisi M, Monical Cal, Petur Dalsgaard, Maurice O Omolo, Hassanali, A., Wenzler, T., Sequin, U., Hamburger, M., Wenzler, Tanja, Tanja Wenzler, Omolo, M. O., Omolo, Maurice O, Hamisi M Malebo, Dalsgaard, P., Cal, M., Häussinger, Daniel, Daniel Häussinger, Häussinger, D., Hamburger, Matthias, Brun, Reto, Sauda M Swaleh, Malebo, H. M., Séquin, Urs, Isaiah O Ndiege, Reto Brun, Cal, Monical, Swaleh, Sauda M, Urs Séquin, Matthias Hamburger   +35 more
core   +2 more sources

Polymorphic Nucleic Acid Binding of Bioactive Isoquinoline Alkaloids and Their Role in Cancer

Journal of Nucleic Acids, 2010
Bioactive alkaloids occupy an important position in applied chemistry and play an indispensable role in medicinal chemistry. Amongst them, isoquinoline alkaloids like berberine, palmatine and coralyne of protoberberine group, sanguinarine of the ...
Motilal Maiti, Gopinatha Suresh Kumar
doaj   +1 more source

Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian [PDF]

, 2005
Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae.
Setiawan, Andi, Junichi Tanaka, Andi Setiawan, Tatsuo Higa, Rachmaniar Rachmat, Higa, Tatsuo, Issa, Hamad H., Hamad H. Issa, Agus Trianto, Trianto, Agus, Tanaka, Junichi, Rachmat, Rachmaniar   +11 more
core   +2 more sources

Improved up-and-down procedure for acute toxicity measurement with reliable LD50 verified by typical toxic alkaloids and modified Karber method

BMC Pharmacology and Toxicology, 2022
Background Up-and-down procedure (UDP) was recommended to replace traditional acute toxicity methods. However, it was limited due to the long experimental period (20–42 days).
Yan-Yu Zhang, Yu-Feng Huang, Jie Liang, Hua Zhou   +3 more
doaj   +1 more source

Soil-borne microorganisms and soil-type affect pyrrolizidine alkaloids in Jacobaea vulgaris [PDF]

, 2009
Secondary metabolites like pyrrolizidine alkaloids (PAs) play a crucial part in plant defense. We studied the effects of soil-borne microorganisms and soil-type on pyrrolizidine alkaloids in roots and shoots of Jacobaea vulgaris.
Veen, J.A., van, Klinkhamer, P.G.L., Joosten, L., Mulder, P.P.J.   +3 more
core   +1 more source