Results 41 to 50 of about 6,408 (192)

Anticancer Potential of Natural Isoquinoline Alkaloid Berberine

Journal of Exploratory Research in Pharmacology, 2021
Despite the availability of several therapeutic strategies and many drugs, the ability to cure most cancers remains a challenge. Natural products have been used for the treatment of numerous diseases, including cancer. The present review delineates various preclinical studies performed in vitro and in vivo that explore the anticancer potential of ...
openaire   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Berberine and Palmatine Distribution Across Plant Organs in Berberis darwinii: Basis for Selecting Superior-Producing Accessions

Molecules
Berberis darwinii, known for its bioactive alkaloids like berberine and palmatine, has gained attention for its medicinal properties. However, comprehensive studies on the specific bioactive molecules of Michay are lacking, as previous research has ...
Manuel Chacón-Fuentes, César Burgos-Díaz, Mauricio Opazo-Navarrete, Alan Mercado, Fernando Westermeyer   +4 more
doaj   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Chemical Composition of Celandine (Chelidonium majus L.) Extract and its Effects on Botrytis tulipae (Lib.) Lind Fungus and the Tulip

, 2013
In this study, the content of chelidonine and berberine alkaloids, and sterols and phenols in the Chelidonium majus plant extract were analyzed. Subsequently, the effects of the extract on the germination and growth of Botrytis tulipae fungus on ...
Ovidiu PARVU, Lucian BARBU-TUDORAN, Alina Elena PARVU, Laszlo FODORPATAKI, PARVU, Ovidiu, VLASE, Laurian, BARBU-TUDORAN, Lucian, PARVU, Alina Elena, Marcel PARVU, FODORPATAKI, Laszlo, BARTHA, Csaba, Laurian VLASE, ROSCA-CASIAN, Oana, Oana ROSCA-CASIAN, Csaba BARTHA, PARVU, Marcel   +15 more
core   +2 more sources

A comparative study of alkaloid and phenolic compounds in different organs and tissues of Berberis integerrima.

PLoS ONE
Berberis integerrima Bunge is a valuable plant of the Berberidaceae family used in medicine and industry. The properties of the different parts of this plant vary and depend on the distribution of its secondary metabolites, including alkaloids and ...
Nastaran Zhaleh, Mohsen Sharifi, Elaheh Samari, Mohammad Reza Halvagar, Seyedeh Hanieh Zeidi   +4 more
doaj   +1 more source

Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)

Molecules, 2008
The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55 alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and piperidine type was studied by measuring DNA fragmentation and changes
Michael Wink, Vera Rosenkranz
doaj   +1 more source

Analysis of glutathione-S-transferases from larvae of Galleria mellonella (Lepidoptera, Pyralidae) with potential alkaloid detoxification function

Frontiers in Physiology, 2022
The greater wax moth, Galleria mellonella, is a global pest for beehives, doing damage in the larval stage. Although a significant number of studies have reported on larvae and adults, to date no effective pest control has been implemented. In this study,
Herbert Venthur, Herbert Venthur, Paula Lizana, Loreto Manosalva, Valentina Rojas, Ricardo Godoy, Adonis Rocha, Iván Aguilera, Rubén Palma-Millanao, Victor Fajardo, Andrés Quiroz, Andrés Quiroz, Ana Mutis, Ana Mutis   +13 more
doaj   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source