Results 51 to 60 of about 81,348 (224)

Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor [PDF]

, 2011
Berberine, an isoquinoline alkaloid derived from plants, is a traditional medicine for treating bacterial diarrhea and intestinal parasite infections. Although berberine has recently been shown to suppress growth of several tumor cell lines, information ...
Tianhui Hu, Rupesh Chaturvedi, Yan Shi, Hamwei Cao, Fang Yan, Lihong Wang, Liping Liu, Keith Wilson, D. Brent Polk   +8 more
core  

A comparative study of alkaloid and phenolic compounds in different organs and tissues of Berberis integerrima.

PLoS ONE
Berberis integerrima Bunge is a valuable plant of the Berberidaceae family used in medicine and industry. The properties of the different parts of this plant vary and depend on the distribution of its secondary metabolites, including alkaloids and ...
Nastaran Zhaleh, Mohsen Sharifi, Elaheh Samari, Mohammad Reza Halvagar, Seyedeh Hanieh Zeidi   +4 more
doaj   +1 more source

Nutrition and Metabolic Diseases: A Systematic Review of Functional Foods, Medicinal Plants, Phytochemicals, Bioactive Compounds and Nutrients Effective Against Metabolic Diseases

Food Chemistry International, EarlyView.
The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi, Sana Noreen, Sonia Morya   +2 more
wiley   +1 more source

The Effects of Berberine and Nitroxl (HNO) on the Glucose Uptake in L929 Fibroblast Cells [PDF]

, 2012
Berberine, which has a long history of use in Chinese medicine, has recently been shown to have efficacy in the treatment of diabetes. While the hypoglycemic effect of berberine has been clearly documented in animal and cell line models, such as 3T3-L1 ...
Chenge, Jude Terver-Jeremiah
core  

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

iNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)

Molecules, 2008
The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55 alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and piperidine type was studied by measuring DNA fragmentation and changes
Michael Wink, Vera Rosenkranz
doaj   +1 more source

Analysis of glutathione-S-transferases from larvae of Galleria mellonella (Lepidoptera, Pyralidae) with potential alkaloid detoxification function

Frontiers in Physiology, 2022
The greater wax moth, Galleria mellonella, is a global pest for beehives, doing damage in the larval stage. Although a significant number of studies have reported on larvae and adults, to date no effective pest control has been implemented. In this study,
Herbert Venthur, Herbert Venthur, Paula Lizana, Loreto Manosalva, Valentina Rojas, Ricardo Godoy, Adonis Rocha, Iván Aguilera, Rubén Palma-Millanao, Victor Fajardo, Andrés Quiroz, Andrés Quiroz, Ana Mutis, Ana Mutis   +13 more
doaj   +1 more source

Structural modification of berberine alkaloid and their hypoglycemic activity

Journal of Functional Foods, 2014
Berberine (BBR), a major active component of natural plant product, has recently been demonstrated to be clinically effective in alleviating type 2 diabetes mellitus (T2DM). In this study, BBR and 8-alkylberberine were successively halogenated with bromine, iodine, chlorine under various conditions.
Yangping Ding, Xiaoli Ye, Jiaying Zhu, Xiaokang Zhu, Xuegang Li, Bingcan Chen   +5 more
openaire   +2 more sources

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source

Binding of Isoquinoline Alkaloids Berberine, Palmatine and Coralyne to Hemoglobin: Sructural and Thermodynamic Characterization Studies

, 2013
Berberine, palmatine and coralyne, the isoquinoline alkaloids distributed in many botanical families, are extensively investigated due to their potential therapeutic actions and clinical utilities.
Hossain, Maidul, Hazra, Soumitra, Kumar, G Suresh   +2 more
core   +1 more source