Results 31 to 40 of about 6,408 (192)

Berberine enhances the anti-hepatocellular carcinoma effect of NK92-MI cells through inhibiting IFN-gamma-mediated PD-L1 expression

Liver Research, 2022
Background and aims: Berberine is one of the most promising clinically tested natural alkaloids, and immunotherapy using natural killer (NK) cells is a potentially effective treatment for hepatocellular carcinoma (HCC).
Kunyuan Wang, Chengxin Gu, Ganxiang Yu, Jiaen Lin, Zhilei Wang, Qianting Lu, Yangzhi Xu, Dan Zhao, Xiaofeng Jiang, Weijian Mai, Shiming Liu, Hui Yang   +11 more
doaj   +1 more source

Anti-Acetylcholinesterase Activities of Mono-Herbal Extracts and Exhibited Synergistic Effects of the Phytoconstituents: A Biochemical and Computational Study

Molecules, 2019
Alzheimer’s disease (AD), a neurodegenerative disease, is the most common form of dementia. Inhibition of acetylcholinesterase (AChE) is a common strategy for the treatment of AD. In this study, aqueous, hydro-methanolic, and methanolic extracts of
Acharya Balkrishna, Subarna Pokhrel, Meenu Tomer, Sudeep Verma, Ajay Kumar, Pradeep Nain, Abhishek Gupta, Anurag Varshney   +7 more
doaj   +1 more source

Aggregation of DNA Enhanced by the Protoberberine Alkaloids, Coralyne and Berberine.

Chemical and Pharmaceutical Bulletin, 1994
The aggregation of DNA caused by coralyne was studied by spectroscopic, viscosity and electric birefringence measurements. Aggregation was markedly enhanced over a narrow range of coralyne to DNA phosphate ratio and then followed by precipitation.
TAIRA, Zenei, MATSUMOTO, Mitsuhiro, ISHIDA, Shiro, ICHIKAWA, Tsutomu, SAKIYA, Yoko   +4 more
openaire   +3 more sources

PREPARATIVE SEPARATION OF ISOQUINOLINE ALKALOIDS FROM PHELLODENDRI CORTEX BY PH-ZONE-REFINING COUNTER-CURRENT CHROMATOGRAPHY

Química Nova
pH-Zone-refining counter-current chromatography (PZRCCC) was successfully used for preparative separation isoquinoline alkaloids from Phellodendri Cortex.
Daijie Wang, Shanming Tian, Li Cui, Huijiao Yan, Xiangyun Song, Yuguo Liu, Fei Xu, Junjian Ma   +7 more
doaj   +1 more source

Nano strategies for berberine delivery, a natural alkaloid of Berberis

Biomedicine & Pharmacotherapy, 2018
Berberine, as a phytochemical component of some medicinal Chinese herbs (most frequently Berberis vulgaris), is an isoquinoline alkaloid with many therapeutic effects including anti-viral, anti-microbial, anti-diarrhea, anti-inflammatory and anti-tumor effects.
Elaheh, Mirhadi, Mehdi, Rezaee, Bizhan, Malaekeh-Nikouei   +2 more
openaire   +2 more sources

Strategies for Identification and Mitigation of Sanguinarine in Mustard Oil Adulterated by Argemone—A Comprehensive Review

Food Chemistry International, EarlyView.
Sanguinarine, a toxic alkaloid present in argemone, can lead to epidemic dropsy or chronic diseases through DNA intercalation and immune system suppression. Regulatory efforts face challenges due to economic motivations for adulteration as well as technical, social, and infrastructure barriers.
Gururaj Pejavara Narayana, Subhangi Panigrahi, Suresh Kumar Kalakandan, Hema Vincent, Ashish Rawson   +4 more
wiley   +1 more source

Interaction of Herbal Compounds with Biological Targets: A Case Study with Berberine

The Scientific World Journal, 2012
Berberine is one of the main alkaloids found in the Chinese herb Huang lian (Rhizoma Coptidis), which has been reported to have multiple pharmacological activities.
Xiao-Wu Chen, Yuan Ming Di, Jian Zhang, Zhi-Wei Zhou, Chun Guang Li, Shu-Feng Zhou   +5 more
doaj   +1 more source

Inhibition of In-vitro Lymphocyte Transformation by the Isoquinoline Alkaloid Berberine

Journal of Pharmacy and Pharmacology, 1995
Abstract Berberine is an isoquinoline alkaloid with multiple pharmacological actions, including an anti-inflammatory activity. The effects of berberine on in-vitro cellular proliferation of human peripheral lymphocytes stimulated with phytohaemagglutinin, concanavalin A and pokeweed mitogen were studied.
K, Ckless, J L, Schlottfeldt, M, Pasqual, P, Moyna, J A, Henriques, M, Wajner   +5 more
openaire   +2 more sources

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

iNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

A Review on Anticancer Potential of Berberis aristata and Berberine with Focus on Quantitative Methods

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022
Berberis aristata (BA) is a traditional herbal ayurvedic medicine widely used from ancient time and has various therapeutic effect. In this review, we had tried to emphasize on its pharmacognistic as well phytochemical parameters.
Manasi Rokade, Vijaya Vichare, Tejaswini Neve, Bhagyashri Parande, Shashikant Dhole   +4 more
doaj   +1 more source