Results 11 to 20 of about 10,438 (226)

Biological Response Profiling Reveals the Functional Differences of Main Alkaloids in Rhizoma Coptidis

Molecules, 2021
Rhizoma Coptidis (RC) is a widely used traditional Chinese medicine. Although modern research has found that some alkaloids from RC are the pharmacologically active constituents, the differences in their biological effects are not completely clear.
Lan Xie, Shanshan Feng, Xiaoling Zhang, Wenlong Zhao, Juan Feng, Chengmei Ma, Ruijun Wang, Weifang Song, Jing Cheng   +8 more
doaj   +1 more source

Coptis alkaloids improve gluconeogenesis and lipid accumulation in mouse primary hepatocytes [PDF]

Jichu yixue yu linchuang, 2023
Objective To screen the alkaloid monomer of coptis chinensis, which can improve the gluconeogenesis and lipid accumulation of mouse primary hepatocytes, and to explore its mechanism.Methods The mouse primary hepatocytes were isolated and incubated with ...
YAN Jiaqi, WANG Siqi, WANG Zheng, LI Jun
doaj   +1 more source

A Review of Fibraurea tinctoria and Its Component, Berberine, as an Antidiabetic and Antioxidant

Molecules, 2023
Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia caused by resistance to insulin action, inadequate insulin secretion, or excessive glucagon production. Numerous studies have linked diabetes mellitus and oxidative stress.
Indah Purwaningsih, Iman Permana Maksum, Dadan Sumiarsa, Sriwidodo Sriwidodo   +3 more
doaj   +1 more source

Preparative separation of three isoquinoline alkaloids from Berberidis radix by pH-zone-refining countercurrent chromatography [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2018
Berberidis radix, as a traditional Chinese herbal medicine, is well known as the main source of berberine. This herbal medicine has been used for the treatment of many diseases and alkaloids including jatrorrhizine, palmatine, and berberine are major ...
Sun Changlei, Zhao Wei, Duan Wenjuan, Yang Peng, Yang Bingtian, Jiang Jiaojiao, Li Jia, Wang Xiao   +7 more
doaj   +1 more source

Berberine: a comprehensive Approach to combat human maladies

International Journal of Food Properties, 2023
Berberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher ...
Zarina Mushtaq, Muhammad Imran, Farhan Saeed, Ali Imran, Shinawar Waseem Ali, Muhammad Shahbaz, Suliman A. Alsagaby, Yolanda Guerrero Sánchez, Maryam Umar, Muzzamal Hussain, Waleed Al Abdulmonem, Entessar Al Jbawi, Mahwish, Ahmed H. El-Ghorab, Mohamed A. Abdelgawad   +14 more
doaj   +1 more source

In Vitro Analyses of the Multifocal Effects of Natural Alkaloids Berberine, Matrine, and Tabersonine against the O’nyong-nyong Arthritogenic Alphavirus Infection and Inflammation

Pharmaceuticals, 2023
O’nyong-nyong virus (ONNV) is a member of the reemerging arthritogenic alphaviruses that cause chronic debilitating polyarthralgia and/or polyarthritis via their tropism for the musculoskeletal system.
Anne-Laure Sandenon Seteyen, Pascale Guiraud, Philippe Gasque, Emmanuelle Girard-Valenciennes, Jimmy Sélambarom   +4 more
doaj   +1 more source

Dose-dependent effects of melatonin on berberine production, antioxidant activity, and metabolite profiles in Berberis vulgaris L. suspension cultures. [PDF]

Sci Rep
Melatonin is a regulatory molecule that increases secondary metabolite biosynthesis in plants. Berberis vulgaris L. is a well-known medicinal plant, valued for its alkaloids and phenolic compounds.
Zeidi SH, Sharifi M, Samari E, Ghanati F, Niknam V, Zhaleh N.   +5 more
europepmc   +2 more sources

Molecular Docking and Dynamics of SARS-CoV-2 Programmed Ribosomal Frameshifting RNA and Ligands for RNA-Targeting Alkaloids Prospecting

Hayati Journal of Biosciences, 2023
RNA-ligand docking is a part of computational biology, which is currently lowly recognized compared to the protein-ligand docking procedure commonly applied for drug discovery.
Adhityo Wicaksono, Arli Aditya Parikesit   +1 more
doaj   +1 more source

Alkaloid Biosynthesis in the Early Stages of the Germination of Argemone mexicana L. (Papaveraceae)

Plants, 2021
The synthesis of the benzylisoquinoline alkaloids, sanguinarine and berberine, was monitored in Argemone mexicana L. (Papaveracea) throughout the early stages of its hypocotyl and seedling development.
Jorge Xool-Tamayo, Yahaira Tamayo-Ordoñez, Miriam Monforte-González, José Armando Muñoz-Sánchez, Felipe Vázquez-Flota   +4 more
doaj   +1 more source

Biological Activity of Berberine—A Summary Update

Toxins, 2020
Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids with strong biological and pharmacological activity. Currently, berberine is receiving considerable interest due to its anticancer activity based on many biochemical ...
Anna Och, Rafał Podgórski, Renata Nowak   +2 more
doaj   +1 more source