Results 11 to 20 of about 6,408 (192)

Berberine: a comprehensive Approach to combat human maladies

International Journal of Food Properties, 2023
Berberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher ...
Zarina Mushtaq, Muhammad Imran, Farhan Saeed, Ali Imran, Shinawar Waseem Ali, Muhammad Shahbaz, Suliman A. Alsagaby, Yolanda Guerrero Sánchez, Maryam Umar, Muzzamal Hussain, Waleed Al Abdulmonem, Entessar Al Jbawi, Mahwish, Ahmed H. El-Ghorab, Mohamed A. Abdelgawad   +14 more
doaj   +1 more source

In Vitro Analyses of the Multifocal Effects of Natural Alkaloids Berberine, Matrine, and Tabersonine against the O’nyong-nyong Arthritogenic Alphavirus Infection and Inflammation

Pharmaceuticals, 2023
O’nyong-nyong virus (ONNV) is a member of the reemerging arthritogenic alphaviruses that cause chronic debilitating polyarthralgia and/or polyarthritis via their tropism for the musculoskeletal system.
Anne-Laure Sandenon Seteyen, Pascale Guiraud, Philippe Gasque, Emmanuelle Girard-Valenciennes, Jimmy Sélambarom   +4 more
doaj   +1 more source

Structural Elucidation and Engineering of the (S)-scoulerine 2-O-Methyltransferase Enabling Regioselective Epiberberine Biosynthesis in Coptis chinensis. [PDF]

Plant Biotechnol J
ABSTRACT Protoberberine alkaloids are a characteristic group of natural products in Coptis plants known for their notable pharmacological activities. However, the structural similarity and the substrate promiscuity of their biosynthetic enzymes have left the precise synthetic pathways remain unclarified, posing challenges to regulate product formation.
Song J, Liu D, Chen S, Tan Y, Wang S, Li S, Qin Y, Li G, Tian X, Yang L, Yuan C, Gou J, Huang W, Chen S, Liu Y.   +14 more
europepmc   +2 more sources

sj-docx-1-npx-10.1177_1934578X211031148 - Supplemental material for Antileishmanial Potential of Berberine Alkaloids From Berberis glaucocarpa Roots: Molecular Docking Suggests Relevant Leishmania Protein Targets

, 2021
Supplemental material, sj-docx-1-npx-10.1177_1934578X211031148 for Antileishmanial Potential of Berberine Alkaloids From Berberis glaucocarpa Roots: Molecular Docking Suggests Relevant Leishmania Protein Targets by Muhammad Alamzeb, Saqib Ali, Mamoon-Ur-
Muhammad Alamzeb (666048), William N. Setzer (7576781), Asad Ullah (4524541), Muhammad Omer (10801819), Saqib Ali (536372), Javed Ali (842820), Akram Shah (11431041), Syed M. Salman (11431038), Ajmal Khan (358733), Behramand Khan (11431035)   +9 more
core   +1 more source

sj-docx-2-npx-10.1177_1934578X211031148 - Supplemental material for Antileishmanial Potential of Berberine Alkaloids From Berberis glaucocarpa Roots: Molecular Docking Suggests Relevant Leishmania Protein Targets

, 2021
Supplemental material, sj-docx-2-npx-10.1177_1934578X211031148 for Antileishmanial Potential of Berberine Alkaloids From Berberis glaucocarpa Roots: Molecular Docking Suggests Relevant Leishmania Protein Targets by Muhammad Alamzeb, Saqib Ali, Mamoon-Ur-
Muhammad Alamzeb (666048), William N. Setzer (7576781), Asad Ullah (4524541), Muhammad Omer (10801819), Saqib Ali (536372), Javed Ali (842820), Akram Shah (11431041), Syed M. Salman (11431038), Ajmal Khan (358733), Behramand Khan (11431035)   +9 more
core   +1 more source

Molecular Docking and Dynamics of SARS-CoV-2 Programmed Ribosomal Frameshifting RNA and Ligands for RNA-Targeting Alkaloids Prospecting

Hayati Journal of Biosciences, 2023
RNA-ligand docking is a part of computational biology, which is currently lowly recognized compared to the protein-ligand docking procedure commonly applied for drug discovery.
Adhityo Wicaksono, Arli Aditya Parikesit   +1 more
doaj   +1 more source

Alkaloid Biosynthesis in the Early Stages of the Germination of Argemone mexicana L. (Papaveraceae)

Plants, 2021
The synthesis of the benzylisoquinoline alkaloids, sanguinarine and berberine, was monitored in Argemone mexicana L. (Papaveracea) throughout the early stages of its hypocotyl and seedling development.
Jorge Xool-Tamayo, Yahaira Tamayo-Ordoñez, Miriam Monforte-González, José Armando Muñoz-Sánchez, Felipe Vázquez-Flota   +4 more
doaj   +1 more source

Biological Activity of Berberine—A Summary Update

Toxins, 2020
Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids with strong biological and pharmacological activity. Currently, berberine is receiving considerable interest due to its anticancer activity based on many biochemical ...
Anna Och, Rafał Podgórski, Renata Nowak   +2 more
doaj   +1 more source

Fungicidal and Herbicidal Activities of Berberine Related Alkaloids

Bioscience, Biotechnology, and Biochemistry, 2000
The 23 quaternary and tertiary protoberberines related to berberine were tested for in vitro and/or in vivo fungicidal and herbicidal activities. Among the compounds tested, there was some activity observed with some of only the protoberberinium salts, but not sufficiently strong or broad spectrum for agrochemical use. From the structure-activity point
IWASA, Kinuko, MORIYASU, Masataka, NADER, Bassam   +2 more
openaire   +2 more sources

An Analysis in Identifying the Mechanism of Action of the Alkaloids Found in on the Treatment and Prevention of SARS-CoV-2

Natural Product Communications, 2023
Introduction Berberis vulgaris extract is a well-known herbal remedy for treating numerous conditions including coronavirus disease 2019 (COVID-19). The HAB4a method of preparing the extract is a common method used in clinical practice and a further aim ...
Samantha Gildenhuys, Paul Anton Steenkamp, Lucas Sekele, Salerwe Mosebi, Chad Clifton James   +4 more
doaj   +1 more source