Results 131 to 140 of about 28,872 (258)
Plant Breeding, EarlyView.ABSTRACT Historically cultivated for medicinal and dyeing purposes, safflower (Carthamus tinctorius L.) saw a shift towards widespread oilseed production after the 1920s due to the growing importance of oils. However, there is a renewed interest in its medicinal and dyeing properties today.
Tansu Uskutoglu +2 more
wiley +1 more source
Novel and emerging antimicrobial strategies in the management of oral infections
Periodontology 2000, EarlyView.Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source
hERG1 channels and potential therapeutics for long QT syndrome
The Journal of Physiology, EarlyView.Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider +3 more
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SGLT2i in heart failure: Cardiorenal mechanisms, clinical evidence and translational perspectives
Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.SGLT2 inhibitors improve heart failure outcomes through integrated cardiorenal mechanisms. In the kidney, they reduce glucose and sodium reabsorption, promoting natriuresis, osmotic diuresis and renal protection. In the heart, they enhance myocardial energetics, reduce inflammation, oxidative stress, fibrosis and adverse remodelling, resulting in fewer
Jelica Grujic‐Milanovic +4 more
wiley +1 more source
, 2019 We previously showed that berberine attenuates MexXY efflux-dependent aminoglycoside resistance in Pseudomonas aeruginosa. Here, we aimed to synthesize berberine derivatives with higher MexXY inhibitory activities. We synthesized 11 berberine derivatives,
Kenta Kotani +7 more
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MicrobiologyOpen, Volume 15, Issue 5, October 2026.The graphical abstract illustrates how microbiome‐derived indoles activate the aryl hydrocarbon receptor to restore the intestinal barrier. The picture contrasts the “leaky gut” state with the restored homeostasis achieved through AMPK, Nrf2, and IL‐22 signaling.
Mohammad Ali Mahdiabadi +2 more
wiley +1 more source
BIOSYNTHESIS OF HYDRASTINE AND BERBERINE [PDF]
The biosynthesis of hydrastine and of berberine was investigated by feeding radioactive tyrosine and dopamine to Hydrastis canadensis L. It was shown that both hydrastine and berberine are specifically derived from two molecules of tyrosine, but that
James, Richard Gear
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Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease
MedComm, Volume 7, Issue 10, October 2026.NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang +9 more
wiley +1 more source
Berberine inhibits human tongue squamous carcinoma cancer tumor growth in a murine xenograft model
, 2012 [[abstract]]Our primary studies showed that berberine induced apoptosis in human tongue cancer SCC-4 cells in vitro. But there is no report to show berberine inhibited SCC-4 cancer cells in vivo on a murine xenograft animal model.
何永?;Ho, YT;楊家欣;Yang, JS;呂啟誠;Lu, CC;江若華;Chiang, JH;李采娟;Li, TC;Lin, JJ;賴光啟;Lai, KC;廖慶隆;Liao, CL;林昭庚;Lin, JG;鍾景光;Chung, Jing-Gung
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Investigation of Berberine Induced Cell Apoptosis in Non-Small Cell Lung Carcinoma NCI-H460 Cells
, 2012 Berberine是一種苦味、黃色、植物異??生物鹼，由黃花、黃柏、黃連萃取出來的，在中藥使用歷史悠久，Berberine 具有廣泛的藥理活性，包括抗增殖、抑制 DNA和蛋白質合成、阻止細胞週期進展和促進癌細胞凋亡的影響。然而，Berberine誘導細胞凋亡的機制並不清楚，過去曾有報導指出Berberine具有抗發炎作用與透過抑制 cyclooxygenase-2 (COX-2) 進而降低前列腺素E2的表現有關。在本研究中，我們也探討Berberine誘導細胞凋亡的機制是否與 COX-2 的活性或是 ...
梁雅琦
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