Results 111 to 120 of about 26,756 (250)
Berberine inhibits angiogenesis in glioblastoma xenografts by targeting the VEGFR2/ERK pathway
Pharmaceutical Biology, 2018 Context: Berberine is used in traditional Chinese medicine for thousands of years with recent reports of its anticancer activity. Objective: To test antiangiogenic effects of berberine on human glioblastoma and clarify involvement of the VEGFR2/ERK ...
Fa Jin +3 more
doaj +1 more source
Cell Proliferation, EarlyView.Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source
Genomic variation drives plant flavor diversification
Journal of Integrative Plant Biology, EarlyView.This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu +5 more
wiley +1 more source
The structure of Berberine hydrochloride. [PDF]
, 2014 The structure of Berberine hydrochloride.
Yuqin Li (561666) +3 more
core +1 more source
Berberine attenuates axonal transport impairment and axonopathy induced by Calyculin A in N2a cells.
PLoS ONE, 2014 Berberine is a primary component of the most functional extracts of Coptidis rhizome used in traditional Chinese medicine for centuries. Recent reports indicate that Berberine has the potential to prevent and treat Alzheimer's disease (AD).
Xiaofeng Liu +7 more
doaj +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Berberine acutely activates the glucose transport activity of GLUT1 [PDF]
, 2011 Berberine, which has a long history of use in Chinese medicine, has recently been shown to have efficacy in the treatment of diabetes. While the hypoglycemic effect of berberine has been clearly documented in animal and cell line models, such as 3T3-L1 ...
Oram, Daniel S. +3 more
core +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Theacrine (1,3,7,9‐tetramethyluric acid) is a purine alkaloid detected in multiple wild and specialised tea germplasms (Camellia sinensis) from South China, including Kucha. However, the molecular mechanisms governing its biosynthesis remain poorly understood. Here, we identify CsTcS2 as a novel theacrine synthase in tea plant.
Ting Wu +13 more
wiley +1 more source
Berberine inhibits human tongue squamous carcinoma cancer tumor growth in a murine xenograft model [PDF]
, 2012 [[abstract]]Our primary studies showed that berberine induced apoptosis in human tongue cancer SCC-4 cells in vitro. But there is no report to show berberine inhibited SCC-4 cancer cells in vivo on a murine xenograft animal model.
何永?;Ho, YT;楊家欣;Yang, JS;呂啟誠;Lu, CC;江若華;Chiang, JH;李采娟;Li, TC;Lin, JJ;賴光啟;Lai, KC;廖慶隆;Liao, CL;林昭庚;Lin, JG;鍾景光;Chung, Jing-Gung
core
Location and identification of berberine in spores. [PDF]
, 2015 (A) DIC images and fluorescence images of individual dormant spores (panes 1, 3), or germinated spores that were incubated in 10 mM L-valine at 23°C for 60 min as described in Methods plus 50 μg/mL of berberine (panes 2, 4).
Milomir Suvira (833933) +4 more
core +1 more source