Results 111 to 120 of about 28,872 (258)
Chinese MedicineBackground Coptidis Rhizoma, the rhizome of Coptis chinensis Franch., has long been employed in the treatment of diabetes. Its active component, berberine, has been utilized in clinical practice; however, the underlying mechanisms of its protective ...
Wei-jian Hang +5 more
doaj +1 more source
Exercise and Berberine Intervention Ameliorate High-Fat Diet-Induced MAFLD by Regulating Gut Microbiota and Hepatic Fatty Acid Beta-Oxidation [PDF]
Xiaojian Zhang,1– 3,* Yanbin Cheng,4,* Qingyu Wei,5 Lixuan Sang,1,2 Quansheng Li5 1Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, 110022, People’s Republic of China; 2College of Exercise and ...
Wei Q, Zhang X, Li Q, Cheng Y, Sang L
core
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
Phytotherapy Research, EarlyView.This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source
BIOSYNTHESIS OF HYDRASTINE AND BERBERINE [PDF]
, 1962 The biosynthesis of hydrastine and of berberine was investigated by feeding radioactive tyrosine and dopamine to Hydrastis canadensis L. It was shown that both hydrastine and berberine are specifically derived from two molecules of tyrosine, but that the
Gear, James Richard
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Experimental Biology and MedicineBerberine, known as an antioxidant agent, can improve glycemic indices in animal models of diabetes; however, it is clinically limited by poor bioavailability.
Yu Liu, Shaik Althaf Hussain, Hua Yue
doaj +1 more source
Phytotherapy Research, EarlyView.Functional dyspepsia involves duodenal barrier dysfunction, low‐grade immune activation and altered neuroimmune signalling. Various plant‐derived bioactives may modulate PPAR signalling, reduce inflammatory and oxidative stress, and support epithelial, immune, metabolic, and sensory homeostasis.
Irene Palenca +5 more
wiley +1 more source
Advances in research on layered double hydroxides for biomedical applications
Smart Molecules, EarlyView.Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
Natural Product Communications, 2017 Berberine, an isoquinoline alkaloid extracted from coptis , exerts anti-proliferation and anticancer properties. Pyruvate kinase M2 (PKM2) is a key enzyme of aerobic glycolysis and considered as the potential anticancer target.
Zhichao Li +4 more
doaj +1 more source
Smart Molecules, EarlyView.An AI‐driven framework integrating disease‐network analysis, direction‐aware molecular screening, and carrier‐free co‐assembly engineering enables nanomedicine design. The dual‐constraint deep learning model predicts API–target affinity and regulatory direction to prioritize complementary APIs.
Kai Xiao +14 more
wiley +1 more source
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
VIEW, EarlyView.This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source