Effects of berberine on proliferation, cell cycle distribution and apoptosis of human breast cancer T47D and MCF7 cell lines [PDF]
Iranian Journal of Basic Medical Sciences, 2015 Objective(s):Berberine, a naturally occurring isoquinoline alkaloid, has shown antitumor properties in some in vitro systems. But the effect of berberine on breast cancer has not yet been completely studied.
Elmira Barzegar +6 more
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Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Scientific ReportsBerberine, a bio-alkaloid from medicinal plants, shows therapeutic potential against various ailments, including cancer. This study evaluated berberine’s effects on the PI3K/Akt pathway and efferocytosis in an adenocarcinoma model to reduce cisplatin ...
Maha M. Salem +4 more
doaj +1 more source
Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms
Phytotherapy Research, EarlyView.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley +1 more source
Berberine inhibits angiogenesis in glioblastoma xenografts by targeting the VEGFR2/ERK pathway
Pharmaceutical Biology, 2018 Context: Berberine is used in traditional Chinese medicine for thousands of years with recent reports of its anticancer activity. Objective: To test antiangiogenic effects of berberine on human glioblastoma and clarify involvement of the VEGFR2/ERK ...
Fa Jin +3 more
doaj +1 more source
Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions
Sensory Neuroscience, EarlyView.ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang +7 more
wiley +1 more source
Effects of Huanglian-Jie-Du-Tang and its modified formula on the modulation of amyloid-β precursor protein processing in Alzheimer's disease models. [PDF]
, 2014 published_or_final_versio
Chen, LL +10 more
core +1 more source
BRD9 inhibition as potential treatment option for testicular germ cell tumors
Andrology, EarlyView.Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen +5 more
wiley +1 more source
Cell Proliferation, EarlyView.In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge +8 more
wiley +1 more source
Evaluation of Inhibitory Effects of Berberine on Apoptosis Due to Measles Virus Strain AIK-HDC
Bihdād, 2012 Background: Measles virus (MV) is a highly contagious agent which causes a major health problem in developing countries. We studied the effect of BERBERINE on the replication of an AIK-HDC strain of MV and its induced apoptosis in Vero cell lines ...
K. Haratian, A. Mohseni Meybodi
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