Results 91 to 100 of about 28,872 (258)
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat +7 more
wiley +1 more source
Berberine showed no cytotoxicity.
Cells were starved in serum-free DMEM supplemented with 0.25% BSA and treated with various doses of berberine or metformin for 24 h. LDH concentrations in medium and cells were detected.
Jun Yin (94374) +8 more
core +1 more source
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Berberine attenuates axonal transport impairment and axonopathy induced by Calyculin A in N2a cells.
Berberine is a primary component of the most functional extracts of Coptidis rhizome used in traditional Chinese medicine for centuries. Recent reports indicate that Berberine has the potential to prevent and treat Alzheimer's disease (AD).
Xiaofeng Liu +7 more
doaj +1 more source
Rhizoma coptidis and berberine-induced activation of murine microglia N9 cells
Aims of the study: To investigate the effect of water extract of Rhizoma coptidis (WEC) and berberine on the activation of murine microglia N9 cells and corresponding mechanism related to ...
Wang, Long-Xing +4 more
core +1 more source
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li +6 more
wiley +1 more source
Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia +1 more
wiley +1 more source
Membrane of Candida albicans as a target of berberine
Background We investigated the mechanisms of anti-Candida action of isoquinoline alkaloid berberine, active constituent of medically important plants of Barberry species.
Nataša Zorić +6 more
doaj +1 more source
Physiological Effects of Berberine [PDF]
Berberine is a well-known plant alkaloid with a long history of medicinal use in Ayurvedic, Chinese, and South Asiantraditional medicine. It can be found in the roots, rhizomes, and the bark of a number of plants.
Wongbutdee, Jaruwan
core
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng +6 more
wiley +1 more source

