Results 101 to 110 of about 26,756 (250)

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li   +6 more
wiley   +1 more source

Evaluation of Inhibitory Effects of Berberine on Apoptosis Due to Measles Virus Strain AIK-HDC

open access: yesBihdād, 2012
Background: Measles virus (MV) is a highly contagious agent which causes a major health problem in developing countries. We studied the effect of BERBERINE on the replication of an AIK-HDC strain of MV and its induced apoptosis in Vero cell lines ...
K. Haratian, A. Mohseni Meybodi
doaj  

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

open access: yesPhytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia   +1 more
wiley   +1 more source

Activation of AMPK by Berberine is ONOO-dependent. [PDF]

open access: yes, 2013
A & B, Effects of adenoviral overexpression of SOD and catalase on Berberine-induced phosphorylation of AMPK-Thr172 and ACC-Ser79 in BAEC. BAEC were transfected with adenovirus overexpressed with SOD, catalase or GFP (50 MOI) for 24 h.
Yingying Han (186431)   +4 more
core   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

open access: yesVIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf   +5 more
wiley   +1 more source

Systematic Investigation of Berberine for Treating Hepatocellular Carcinoma Based on Network Pharmacology

open access: yesDigital Chinese Medicine, 2019
Objective: Liver cancer is the 4th leading cause of cancer death worldwide,and hepatocellular carcinoma (HCC) accounts for the largest proportion of these deaths.
Mu Jie   +7 more
doaj   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen   +5 more
wiley   +1 more source

Nanocarrier-Assisted Delivery of Berberine Promotes Diabetic Alveolar Bone Regeneration by Scavenging ROS and Improving Mitochondrial Dysfunction [PDF]

open access: yes
Ye Ming,1– 3,* Xinyi He,1– 3,* Zhenxing Zhao,1– 3,* Xuehuan Meng,1– 3 Ye Zhu,1– 3 Hao Tan,1– 3 Guoyin Yang,1– 3 Yun Hu,1– 3 Leilei Zheng1– 3 1College of Stomatology, Chongqing Medical University, Chongqing, People’s Republic of China ...
Yang G   +8 more
core   +1 more source

Physiological Effects of Berberine [PDF]

open access: yes, 2009
Berberine is a well-known plant alkaloid with a long history of medicinal use in Ayurvedic, Chinese, and South Asiantraditional medicine. It can be found in the roots, rhizomes, and the bark of a number of plants.
Wongbutdee, Jaruwan
core   +1 more source

13-(2-Methylbenzyl) Berberine Is a More Potent Inhibitor of MexXY-Dependent Aminoglycoside Resistance than Berberine [PDF]

open access: yes, 2019
We previously showed that berberine attenuates MexXY efflux-dependent aminoglycoside resistance in Pseudomonas aeruginosa. Here, we aimed to synthesize berberine derivatives with higher MexXY inhibitory activities. We synthesized 11 berberine derivatives,
Kenta Kotani   +7 more
core   +1 more source

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