Results 61 to 70 of about 60,745 (143)
Molecules, 2018 Berberine has many pharmacological effects, such as antidiabetic, antimicrobial, anti-inflammatory, and antioxidant, but the question remains on how its low oral bioavailability has greatly limited its clinical application. As a safer hypoglycemic agent,
Hong-Xin Cui +4 more
doaj +1 more source
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
VIEW, EarlyView.This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source
Therapeutic potential of Coptis chinensis for arthritis with underlying mechanisms
Frontiers in Pharmacology, 2023 Arthritis is a common degenerative disease of joints, which has become a public health problem affecting human health, but its pathogenesis is complex and cannot be eradicated.
Mengyuan Li +9 more
doaj +1 more source
Advanced Science, Volume 13, Issue 55, 5 October 2026.A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang +11 more
wiley +1 more source
Determination of berberine hydrochloride in tablets (n = 5, p = 95%).
, 2014 Determination of berberine hydrochloride in tablets (n = 5, p = 95%).
Yuqin Li (561666) +3 more
core +1 more source
Pharmaceutics, 2022 Berberine hydrochloride (BRB) is an isoquinoline alkaloid with promising anticancer efficacies. However, application of BRB had been hampered by its poor aqueous solubility, low gastrointestinal absorption, and rapid metabolism.
Abir Salek +5 more
doaj +1 more source
Advanced Intelligent Discovery, Volume 2, Issue 5, October 2026.This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
Optimization of extraction and clarification technology of Baitouweng oral liquid
Siliao yanjiu, 2023 The study aimed to optimize the extraction and clarification process of Baitouweng oral liquid. The L9(34) orthogonal test was used to optimize the water extraction and clarification process of Baitouweng oral liquid.
HAN Ru-shuo +7 more
doaj
MedComm, Volume 7, Issue 8, August 2026.Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong +8 more
wiley +1 more source
Hypothesis-Generating Brief: Berberine hydrochloride — full paper
Researka accepted publication: a1f46e6e-cd1b-40a7-8641-5b96e4526923 Source submission: 6f0113a2-1cfe-44a3-9477-90e14d164f8b This paper synthesizes evidence on Berberine hydrochloride across 35 accepted source papers and 1902 high-confidence extracted ...
Dominic Lynch
core +6 more sources