Results 201 to 210 of about 79,849 (298)

4‐Ethyl phenyl sulfate binding to human serum albumin

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Protein‐bound uremic toxins (PBUTs) such as 4‐ethylphenyl sulfate (4‐EPS) challenge kidney failure management due to strong binding to human serum albumin (HSA), thus limiting dialysis clearance. This study examined 4‐EPS–HSA interactions using saturation transfer difference nuclear magnetic resonance spectroscopy (STD‐NMR), isothermal ...
Vida Dehghan Niestanak, Jacopo Zattoni, Ryan T. McKay, Marcello Tonelli, Maral Aminpour, Larry D. Unsworth   +5 more
wiley   +1 more source

Association Between Medicare Drug Plan Ratings and Coverage Barriers for Non-Generic, Evidence-Based Cardiovascular Medications. [PDF]

Circ Popul Health Outcomes
Adelsheimer A, Hoffer-Hawlik M, Ladino N, Adhikari S, Zhang DS, P Squires A, Berman AN, D Katz S, R Reynolds H, Blecker S, Mukhopadhyay A.   +10 more
europepmc   +1 more source

A simple probabilistic AlphaFold interaction score

Protein Science, Volume 35, Issue 9, September 2026.
Abstract AlphaFold has enabled large‐scale prediction of protein–protein and protein–nucleic acid complexes, but ranking and assessing the quality of predicted models remain challenging. Existing confidence scores are often highly parametrized and provide limited interpretability.
Mihaly Badonyi, Agnes Toth‐Petroczy
wiley   +1 more source

The Roles of Empathy, Proximity, and Identity in Alzheimer's Disease Stigma. [PDF]

Behav Sci (Basel)
Seda A, Mitova E, Stuckey AL, Berman SL.
europepmc   +1 more source

A cofactor‐promiscuous HMGR from the Lyme disease pathogen illuminates diversity in bacterial isoprenoid biosynthesis

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The Lyme disease pathogen Borrelia burgdorferi contains a highly reduced genome lacking many primary metabolic pathways. However, B. burgdorferi retains the mevalonate pathway that synthesizes isopentenyl pyrophosphate (IPP), the precursor to the peptidoglycan carrier lipid.
Isaac A. Paddy, Joshua McCausland, Madelyn Frazier, Poulami Chatterjee, Mekedlawit Setegne, Oliv Eidam, Christine Jacobs‐Wagner, Laura M. K. Dassama   +7 more
wiley   +1 more source

Mechanical dyssynchrony and septal-lateral perfusion heterogeneity predict adverse left ventricular remodelling beyond ECG-defined LBBB. [PDF]

Eur Heart J Cardiovasc Imaging
Brandão SCS, Joseph L, Brown JM, Lopez D, Lemley M, Ramirez G, Kavanagh P, Van Kriekinge SD, Liang J, Builoff V, Divakaran S, Weber B, Hainer J, Carre S, Blankstein R, Dorbala S, Le VT, Mason S, Knight S, Chareonthaitawee P, Wopperer S, Rosamond TL, Berman DS, Dey D, Di Carli MF, Slomka PJ, Huck DM.   +26 more
europepmc   +1 more source

Avoiding pitfalls when modelling ligands in macromolecular crystallography

Acta Crystallographica Section D, Volume 82, Issue 9, Page 1016-1029, September 2026.
Flawed protein–ligand X‐ray structures can misdirect drug discovery based on PDB‐deposited models. This review uses publicly available PDB examples to highlight potential pitfalls, from absent ligands to incorrect chemistry, and presents a practical validation approach to improve model reliability.The determination of protein–ligand complex structures ...
Oliver S. Smart, Andrew Sharff, Claus Flensburg, Clemens Vonrhein, Gérard Bricogne   +4 more
wiley   +1 more source

Association of caffeine levels with myocardial perfusion during pharmacological stress cardiac magnetic resonance imaging. [PDF]

Am Heart J Plus
Iribarren A, Obrutu O, Maughan J, Cook-Wiens G, Bairey Merz CN, Li D, Berman DS, Kwan AC, Wei J.   +8 more
europepmc   +1 more source

Fluid Toxicities: Violent Affective Ecologies in Cartagena, Colombia

Antipode, Volume 58, Issue 5, September 2026.
ABSTRACT Water is at the centre of climate change emergency concerns in coastal cities. It constitutes here a fluid entry point to investigating the socio‐ecological politics of toxicities for residents dwelling with and against contaminated waters in Cartagena, Colombia's urban extensions.
Laura Neville, Silke Oldenburg
wiley   +1 more source