Results 41 to 50 of about 220,874 (298)

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Improved approximation algorithms for optimization problems in graphs with superlogarithmic treewidth

open access: yes, 2003
In this paper we present two novel generic schemes for approximation algorithms for optimization to partial k-trees. Our first scheme yields deterministic polynomialtime algorithms achieving typically an approximation factor of k/ log n, where k
Chlebikova, Janka   +14 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

On best approximations to compact operators [PDF]

open access: yesProceedings of the American Mathematical Society, 2021
We study best approximations to compact operators between Banach spaces and Hilbert spaces, from the point of view of Birkhoff-James orthogonality and semi-inner-products. As an application of the present study, some distance formulae are presented in the space of compact operators. The special case of bounded linear functionals as
openaire   +3 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Improved Best-fitting Gaussian Approximation PHD Filter

open access: yesLeida xuebao, 2013
The best-fitting Gaussian approximation Probability Hypothesis Density (PHD) filter is a novel algorithm for multiple maneuvering target tracking. However, there is a problem that the model probabilities are calculated without the measurement innovation.
Ouyang-Cheng, Chen Xiao-xu, Hua Yun
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Extensions of best approximation and coincidence theorems

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1997
Let X be a Hausdorff compact space, E a topological vector space on which E* separates points, F:X→2E an upper semicontinuous multifunction with compact acyclic values, and g:X→E a continuous function such that g(X) is convex and g−1(y) is acyclic for ...
Sehie Park
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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