Results 61 to 70 of about 199,729 (254)

On the best approximation in metric spaces

open access: yesJournal of Numerical Analysis and Approximation Theory, 1975
Not available.
Costică Mustăţa
doaj   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Interpolation and best simultaneous approximation

open access: yesJournal of Approximation Theory, 2010
The paper deals with best simultaneous approximation (b.s.a.) to \(k\) continuous functions on the interval \([a,b]\) from a finite subspace of \(C[a,b]\). The authors establish the limit of the b.s.a., which is important to provides qualitative and approximation analytic information concerning the the b.s.a.
Héctor Cuenya, Fabián E. Levis
openaire   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Ambulatory blood pressure data is the best approximation of central aortic pressure in coarctation of aorta. [PDF]

open access: yesInt J Cardiol Congenit Heart Dis, 2021
Egbe AC   +3 more
europepmc   +1 more source

Best Approximation and Best Co-Approximation in Normed Space

open access: yes, 2009
In this thesis, the concept of best approximation and best co-approximation in normed linear spaces is studied. The concepts of ε-best approximation and ε-best co-approximation and ε-orthogonality are introduced and the relations between these concepts are obtained. Also the maps which preserve approximation are discussed. Some results are studied. For
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Phelps type duality results in best approximation

open access: yesJournal of Numerical Analysis and Approximation Theory, 2002
The aim of the present paper is to show that many Phelps type duality result, relating the extension properties of various classes of functions (continuous, linear continuous, bounded bilinear, Hölder-Lipschitz) with the approximation properties ...
Ştefan Cobzaş
doaj   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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