Results 61 to 70 of about 5,291,016 (330)

Novel Presenting Phenotype in a Child With Autosomal Dominant Best's Vitelliform Macular Dystrophy

open access: yesOphthalmic Surgery, Lasers and Imaging Retina, 2017
Best's macular dystrophy (BMD) usually manifests with visual failure in the first or second decade of life; however, there is a large variability in expressivity of the disease, and some patients have no manifestation other than a pathological electro-oculogram (EOG). Autosomal dominant Best's vitelliform macular dystrophy (AD-BVMD) has a very specific
Abdalla, Yasmine F.   +3 more
openaire   +5 more sources

Common best proximity points for a pair of mappings with certain dominating property

open access: yesDemonstratio Mathematica, 2023
Abstract This article introduces a type of dominating property, partially inherited from L. Chen’s, and proves an existence and uniqueness theorem concerning common best proximity points. A certain kind of boundary value problem involving the so-called Caputo derivative can be formulated so that our result applies.
Phakdi Charoensawan   +2 more
openaire   +3 more sources

Common Best Proximity Coincidence Point Theorem for Dominating Proximal Generalized Geraghty in Complete Metric Spaces [PDF]

open access: yesJournal of Function Spaces, 2020
In this paper, we introduce a new concept of dominating proximal generalized Geraghty for two mappings and prove the existence and uniqueness of a common best proximity coincidence point in complete metric spaces. And also, we give an example for the main theorems. The main theorem is a generalization and improvement of some well-known theorems.
Anchalee Khemphet   +2 more
openaire   +3 more sources

Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations

open access: yesScientific Reports, 2019
BEST1 is a Ca2+-activated Cl− channel predominantly expressed in retinal pigment epithelium (RPE), and over 250 genetic mutations in the BEST1 gene have been identified to cause retinal degenerative disorders generally known as bestrophinopathies.
Changyi Ji   +9 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Monotonicity Properties of Musielak–Orlicz Spaces and Dominated Best Approximation in Banach Lattices

open access: yesJournal of Approximation Theory, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hudzik, H, Kurc, W
openaire   +2 more sources

Structural Convergence Results for Approximation of Dominant Subspaces from Block Krylov Spaces [PDF]

open access: yesSIAM Journal on Matrix Analysis and Applications, 2016
This paper is concerned with approximating the dominant left singular vector space of a real matrix $A$ of arbitrary dimension, from block Krylov spaces generated by the matrix $AA^T$ and the block vector $AX$. Two classes of results are presented. First
P. Drineas   +3 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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