Results 21 to 30 of about 157,278 (142)

In vivo evidence of angiogenesis inhibition by β2-glycoprotein I subfractions in the chorioallantoic membrane of chicken embryos [PDF]

Brazilian Journal of Medical and Biological Research, 2021
The vascular network expansion and functioning are important factors affecting normal intra-uterine fetal development. This study addressed the previously reported antiangiogenic potential of beta-2-glycoprotein I (β2GPI) in vivo in the chick embryo ...
C.M. Baldavira, L.F. Gomes, L.T. De La Cruz, D.A. Maria, V.L. Capelozzi   +4 more
doaj   +1 more source

Changes in the Level of Antiphospholipid Antibodies (Anticardiolipin and Anti-β2-Glycoprotein-I) and Thromboembolic Indices in COVID-19 Patients during 3 Weeks

International Journal of Preventive Medicine, 2023
Introduction: COVID-19 is a respiratory disease caused by infection with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). Thrombotic complications appear to be of particular importance in patients with COVID-19.
Somayeh Haghighipour, Mansour Salesi, Fereshteh Keikhaei, Mohammad J. Tarrahi, Zahra Khani, Hassan Salehi   +5 more
doaj   +1 more source

Pathogenesis of the obstetric antiphospholipid syndrome: the key role of beta 2 glycoprotein I

Exploration of Immunology, 2022
Antiphospholipid syndrome (APS) is defined by recurrent pregnancy morbidity and/or vascular thrombosis associated with the persistent presence of antibodies against anionic phospholipid-binding proteins. Beta 2 glycoprotein I (β2GPI) and prothrombin (PT)
Pier Luigi Meroni, Claudia Grossi, Francesco Tedesco   +2 more
doaj   +1 more source

Consequences of antiphospholipid syndrome in pregnancy - A review [PDF]

Romanian Journal of Rheumatology, 2023
Background and objectives. Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the presence of antiphospholipid antibodies (aPL) in the blood.
Astrit M. Gash
doaj   +1 more source

Zinc Chloride: Time-Dependent Cytotoxicity, Proliferation and Promotion of Glycoprotein Synthesis and Antioxidant Gene Expression in Human Keratinocytes

Biology, 2021
The use of ionic metals such as zinc (Zn2+) is providing promising results in regenerative medicine. In this study, human keratinocytes (HaCaT cells) were treated with different concentrations of zinc chloride (ZnCl2), ranging from 1 to 800 µg/mL, for 3,
Beatriz Salesa, Roser Sabater i Serra, Ángel Serrano-Aroca   +2 more
doaj   +1 more source

Anti-beta 2 glycoprotein I antibodies in centenarians [PDF]

Experimental Gerontology, 2004
Non-organ-specific autoantibodies are present in centenarians without evidence of autoimmune diseases but conflicting or no data on anti-phospholipid and anti-phospholipid binding proteins were reported.To investigate the presence and antigen specificity of anti-phospholipid and anti-phospholipid binding proteins in centenarians.Seventy-seven ...
Meroni P. L., Mari D., Monti D., Coppola R., CAPRI, MIRIAM, SALVIOLI, STEFANO, Tincani A., Gerli R., FRANCESCHI, CLAUDIO   +8 more
openaire   +5 more sources

Dimers of β2-Glycoprotein I Mimic thein Vitro Effects of β2-Glycoprotein I-Anti-β2-glycoprotein I Antibody Complexes [PDF]

Journal of Biological Chemistry, 2001
Anti-beta(2)-glycoprotein I antibodies are thought to cause lupus anticoagulant activity by forming bivalent complexes with beta(2)-glycoprotein I (beta(2)GPI). To test this hypothesis, chimeric fusion proteins were constructed of the dimerization domain (apple 4) of factor XI and beta(2)GPI.
Lutters, B. C., Meijers, J. C., Derksen, R. H., Arnout, J., de Groot, P. G.   +4 more
openaire   +3 more sources

Budd-Chiari Syndrome as an Initial Presentation of Antiphospholipid Syndrome in a Male [PDF]

Journal of Clinical and Diagnostic Research, 2022
In Budd-Chiari Syndrome (BCS) there is narrowing and obstruction of the veins of the hepatic veins. Patients have upper quadrant abdominal pain, hepatomegaly and/or ascites.
Pusala Varun Narayana, Prasanna Kumar Satpathy, S Bharath Gowda, Srivatsav Addepalli   +3 more
doaj   +1 more source

Thrombosis and antiphospholipid antibodies in Japanese COVID-19: based on propensity score matching

Frontiers in Immunology, 2023
BackgroundThrombosis is a unique complication of coronavirus disease 2019 (COVID-19). Although antiphospholipid antibodies (aPL) are detected in COVID-19 patients, their clinical significance remains elusive.
Seiya Oba, Tadashi Hosoya, Risa Kaneshige, Daisuke Kawata, Taiki Yamaguchi, Takahiro Mitsumura, Takahiro Mitsumura, Sho Shimada, Sho Shibata, Tomoya Tateishi, Ryuji Koike, Shuji Tohda, Akihiro Hirakawa, Nukui Yoko, Nukui Yoko, Yasuhiro Otomo, Junzo Nojima, Yasunari Miyazaki, Shinsuke Yasuda   +18 more
doaj   +1 more source

beta 2-Glycoprotein I and anti-beta 2-glycoprotein I antibodies: where are we now? [PDF]

Rheumatology, 1997
beta 2-Glycoprotein I (beta 2-GPI), a plasma protein with in vitro anticoagulant properties, has been recognized to have an important role in the antiphospholipid syndrome (APS) as a cofactor and an (co)antigen in ELISA assays. Although beta 2-GPI levels were found to be increased in some patients with APS, the clinical value of measuring beta 2-GPI ...
openaire   +1 more source