Results 1 to 10 of about 61,616 (183)

Desensitization of the turkey erythrocyte beta-adrenergic receptor in a cell-free system. Evidence that multiple protein kinases can phosphorylate and desensitize the receptor.

Journal of Biological Chemistry, 1985
P Nambi, J R Peters, David R. Sibley, R J Lefkowitz   +3 more
openalex   +2 more sources

Chronic .BETA.-Adrenergic Receptor Stimulation Enhances the Expression of G-Protein Coupled Receptor Kinases, GRK2 and GRK5, in Both the Heart and Peripheral Lymphocytes

Circulation Journal, 2005
Naotsugu Oyama, Kazushi Urasawa, Satoshi Kaneta, Hidetsugu Sakai, Takahiko Saito, Chika Takagi, Ichiro Yoshida, Akira Kitabatake, Hiroyuki Tsutsui   +8 more
openalex   +3 more sources

Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart. [PDF]

Circulation Research, 1994
Martin Ungerer, Giustino Parruti, Michael Böhm, Mechthild Puzicha, Antonio DeBlasi, Erland Erdmann, Martin J. Lohse   +6 more
openalex   +2 more sources

A beta-adrenergic receptor kinase-like enzyme is involved in olfactory signal termination. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1993
Sabine Schleicher, Ingrid Boekhoff, J.L. Arriza, Robert J. Lefkowitz, Heinz Breer   +4 more
openalex   +2 more sources

Regulation of G protein-coupled receptor kinase subtypes in activated T lymphocytes. Selective increase of beta-adrenergic receptor kinase 1 and 2. [PDF]

Journal of Clinical Investigation, 1995
Antonio De Blasi, Giustino Parruti, Michele Sallese   +2 more
openalex   +2 more sources

Protein kinase cross-talk: membrane targeting of the beta-adrenergic receptor kinase by protein kinase C. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1996
Rainer Winstel, Stefan M.V. Freund, Cornelius Krasel, E. Hoppe, Martin J. Lohse   +4 more
openalex   +2 more sources

Oligodeoxynucleotides antisense to mRNA encoding protein kinase A, protein kinase C, and beta-adrenergic receptor kinase reveal distinctive cell-type-specific roles in agonist-induced desensitization. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1994
Meng-Fu Maxwell Shih, C C Malbon
openalex   +2 more sources

Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase.

Proceedings of the National Academy of Sciences of the United States of America, 1991
Neil S. Roth, P. Campbell, M G Caron, R.J. Lefkowitz, Martin J. Lohse   +4 more
openalex   +2 more sources

Silodosin inhibits noradrenaline-activated transcription factors Elk1 and SRF in human prostate smooth muscle. [PDF]

, 2012
The transcription factors Elk1 and serum response factor (SRF) are central regulators of cell cycle and phenotype in various cell types. Elk1 is activated by phosphorylation (serine-383), while activation of SRF requires its co-factor, myocardin ...
Andersson, Karl-Erik, Beckmann, Christer, Füllhase, Claudius, Gratzke, Christian, Hedlund, Petter, Hennenberg, Martin, Montorsi, Francesco, Rutz, Beata, Stief, Christian Georg, Strittmatter, Frank, Waidelich, Raphaela   +10 more
core   +27 more sources

Harmine and 7,8-dihydroxyflavone synergistically suitable for amyotrophic lateral sclerosis management: An in silico study [PDF]

Research Results in Pharmacology, 2022
Introduction: Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease characterized by progressive degeneration of both upper and lower motor neurons, resulting in paralysis and eventually leads to death from respiratory failure typically ...
Toluwase Fatoki, Stanley Chukwuejim, Omodele Ibraheem, Christiana Oke, Blessing Ejimadu, Isaiah Olaoye, Oluwabukola Oyegbenro, Taiwo Salami, Romilola Basorun, Oluwafisayomi Oluwadare, Yetunde Salawudeen   +10 more
doaj   +3 more sources