Results 1 to 10 of about 10,835 (197)

Rat beta-adrenergic receptor kinases 1 and 2 in mouse neuroblastoma X rat glioma NG 10845 hybrid cells [PDF]

Biochemical Pharmacology, 1998
Stefan Müller, Rüdiger Schulz, R Schulz   +2 more
exaly   +2 more sources

Harmine and 7,8-dihydroxyflavone synergistically suitable for amyotrophic lateral sclerosis management: An in silico study [PDF]

Research Results in Pharmacology, 2022
Introduction: Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease characterized by progressive degeneration of both upper and lower motor neurons, resulting in paralysis and eventually leads to death from respiratory failure typically ...
Toluwase Fatoki, Stanley Chukwuejim, Omodele Ibraheem, Christiana Oke, Blessing Ejimadu, Isaiah Olaoye, Oluwabukola Oyegbenro, Taiwo Salami, Romilola Basorun, Oluwafisayomi Oluwadare, Yetunde Salawudeen   +10 more
doaj   +3 more sources

ADAM17, A Key Player of Cardiac Inflammation and Fibrosis in Heart Failure Development During Chronic Catecholamine Stress

Frontiers in Cell and Developmental Biology, 2021
Heart failure development is characterized by persistent inflammation and progressive fibrosis owing to chronic catecholamine stress. In a chronic stress state, elevated catecholamines result in the overstimulation of beta-adrenergic receptors (βARs ...
Joseph Adu-Amankwaah, Gabriel Komla Adzika, Adebayo Oluwafemi Adekunle, Marie Louise Ndzie Noah, Richard Mprah, Aisha Bushi, Nazma Akhter, Fei Huang, Yaxin Xu, Seyram Yao Adzraku, Iqra Nadeem, Hong Sun   +11 more
doaj   +1 more source

Activation of the Thiazide-Sensitive Sodium-Chloride Cotransporter by Beta3-Adrenoreceptor in the Distal Convoluted Tubule

Frontiers in Physiology, 2021
We previously showed that the beta-3 adrenergic receptor (BAR3) is expressed in most segments of the nephron where its agonism promotes a potent antidiuretic effect.
Serena Milano, Monica Carmosino, Andrea Gerbino, Ilenia Saponara, Dominga Lapi, Massimo Dal Monte, Paola Bagnoli, Maria Svelto, Giuseppe Procino   +8 more
doaj   +1 more source

Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart. [PDF]

Circulation Research, 1994
The beta-adrenergic receptor system of the failing human heart is markedly desensitized. We have recently postulated that this desensitization may in part be caused by an increase in beta-adrenergic receptor kinase (beta ARK) expression. beta ARK is thought to effect desensitization by acting in concert with an inhibitor protein, called beta-arrestin ...
Böhm M, Puzicha M, Erdmann E, Lohse MJ, DE BLASI, ANTONIO, Parruti G, Ungerer M   +6 more
core   +5 more sources

Rhodopsin kinase activity modulates the amplitude of the visual response in Drosophila [PDF]

, 2019
A feature shared between Drosophila rhodopsin and nearly all other G protein-coupled receptors is agonist-dependent protein phosphorylation. Despite extensive analyses of Drosophila photo-transduction, the identity and function of the rhodopsin kinase ...
Lee, SJ, Montell, C, Xu, H
core   +1 more source

Identification of a short sequence highly divergent between beta-adrenergic-receptor kinases 1 and 2 that determines the affinity of binding to beta gamma subunits of heterotrimeric guanine-nucleotide-binding regulatory proteins [PDF]

, 1997
A 28-residue peptide (peptide G), derived from the C-terminal (W643-S670) of the beta-adrenergic receptor kinase (beta ARK), was previously identified as the critical domain for binding to the beta gamma subunits fo the heterotrimeric guanine-nucleotide ...
POMPILI, Elena, Lina Paolucci, DE BLASI, ANTONIO, Mario Salmona, Tsu Tshen Chuang, L. De Gioia, Michele Sallese   +6 more
core   +1 more source

Effect of the gut microbiota metabolite phenylacetylglycine on cardiac Ca²⁺ signaling. [PDF]

Biophys Rep (N Y)
Bovo E, Zima AV.
europepmc   +1 more source

Targeted Therapies in Infantile Hemangiomas and Vascular Malformations: From β-Blockers to PI3K/AKT/mTOR Inhibitors. [PDF]

J Cell Mol Med
Arasiewicz H, Dec M.
europepmc   +1 more source

Cross-Talk Between Signaling and Transcriptional Networks Regulating Thermogenesis-Insights into Canonical and Non-Canonical Regulatory Pathways. [PDF]

Int J Mol Sci
Simka-Lampa K.
europepmc   +1 more source