Results 131 to 140 of about 61,745 (283)

Beta-agonist- and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors.

, 1986
R. H. Strasser, Jeffrey Benovic, Marc G. Caron, Robert J. Lefkowitz   +3 more
openalex   +1 more source

Src Regulates Sequence‐Dependent Beta‐2 Adrenergic Receptor Recycling via Cortactin Phosphorylation

Traffic : the International Journal of Intracellular Transport, 2014
R. Vistein, M. Puthenveedu
semanticscholar   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

β‐Adrenergic Receptor Activation Modulates the Induction of Complex Spike‐Dependent LTP by Regulating Multiple Forms of Heterosynaptic Plasticity

Hippocampus, Volume 35, Issue 6, November 2025.
ABSTRACT Norepinephrine, acting through β‐adrenergic receptors (β‐ARs), has a key role in hippocampus‐dependent forms of learning. Although β‐AR activation also facilitates the induction of Hebbian LTP, recent findings indicate that a non‐Hebbian form of synaptic plasticity, known as behavioral timescale synaptic plasticity (BTSP), underlies ...
Thomas J. O'Dell
wiley   +1 more source

Salusin‐β, Arterial Stiffness, and Heart Rate Variability Influence the Blood Pressure Response to High‐Intensity Interval Training Among Older Adults With Hypertension: A Randomized Control Trial

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims Salusin‐α and ‐β are two isoforms with opposing effects on the etiology of hypertension. We examined the effects of salusin‐α and ‐β, carotid‐femoral pulse wave velocity (cfPWV), and heart rate variability (HRV) on the blood pressure (BP) response to high‐intensity interval training (HIIT).
Alireza Ghardashi‐Afousi, Linda S. Pescatello, Maryam Asvadi Fard, Aida Sabouri   +3 more
wiley   +1 more source

Desensitization of the human beta 1-adrenergic receptor. Involvement of the cyclic AMP-dependent but not a receptor-specific protein kinase.

, 1991
Xuan Zhou, Peter H. Fishman
openalex   +1 more source

Histone H3 Lysine 18 Lactylation Promotes Cardiac Hypertrophy Through Activating GATA Binding Protein 4 Signaling

MedComm, Volume 6, Issue 11, November 2025.
Proposed model of the interaction of the H3K18la lactylation with GATA4 to promote the cardiac hypertrophy. The image was created using Home for Researchers.com. ABSTRACT Histone lactylation, particularly histone H3 lysine 18 lactylation (H3K18la), modulates gene expression profile in diverse cellular processes, which has emerged as a critical factor ...
Mingzhu Wang, Zixian Liu, Yongbo Ma, Da Li, Yuan Lin, Yani Wang, Deyu Fu, Haidong Guo, Liang Hu   +8 more
wiley   +1 more source

Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
ABSTRACT Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, including endothelial cells, produce cyanide endogenously, where it can modulate mitochondrial bioenergetics ...
Elif Alan‐Albayrak, Ulf Simonsen
wiley   +1 more source

Is Adipose Tissue Inflammation the Culprit of Obesity‐Associated Comorbidities?

Obesity Reviews, Volume 26, Issue 11, November 2025.
ABSTRACT In individuals with obesity, the onset of chronic comorbidities coincides with the excessive accumulation of adipose tissue in various tissue beds. As obesity progresses, adipose tissue becomes increasingly dysfunctional causing chronic low‐grade inflammation.
Laurent Turner, Anjalee I. Wanasinghe, Pamela Brunori, Sylvia Santosa   +3 more
wiley   +1 more source

Modulation of the Neurovascular Unit by the Locus Coeruleus–Norepinephrine System: From Physiological Mechanisms to Therapeutic Applications

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
The locus coeruleus (LC)–norepinephrine (NE) system significantly influences the structure and function of the neurovascular unit (NVU). The activation degree and firing patterns of LC–NE neurons, as well as the release amount and action sites of NE, profoundly impact the neurons, glial cells, and cerebrovascular components of the NVU.
Zixin Pan, Zhaoxing Jia, Tianxiang Jiang, Qian Cai, Zhong Di, Lin Gan, Congcong Ma, Xianming Lin   +7 more
wiley   +1 more source