Results 191 to 200 of about 28,675 (270)

Chronic .BETA.-Adrenergic Receptor Stimulation Enhances the Expression of G-Protein Coupled Receptor Kinases, GRK2 and GRK5, in Both the Heart and Peripheral Lymphocytes

, 2005
Naotsugu Oyama, Kazushi Urasawa, Satoshi Kaneta, Hidetsugu Sakai, Takahiko Saito, Chika Takagi, Ichiro Yoshida, Akira Kitabatake, Hiroyuki Tsutsui   +8 more
openalex   +2 more sources

Trained Immunity and Cardiovascular Risk: An Immunological Perspective

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Systemic inflammation is a key driver of atherogenesis and its complications. While anti‐inflammatory therapies targeting pathways such as IL‐1β and IL‐6 have shown promise in established atherosclerotic cardiovascular disease (ASCVD), potential systemic effects raise concerns about immune suppression and infection, underscoring the need for ...
Katherine A. Boden, Jason Chai, Tafadzwa T. J. Kufazvinei, Robin P. Choudhury   +3 more
wiley   +1 more source

ActSeek: fast and accurate search algorithm of active sites in alphafold database. [PDF]

Bioinformatics
Castillo S, Ollila OHS.
europepmc   +1 more source

Specific enhancement of beta-adrenergic receptor kinase activity by defined G-protein beta and gamma subunits.

, 1993
Sabine Müller, Mirko Hekman, Martin J. Lohse   +2 more
openalex   +2 more sources

Familial Cerebral Cavernous Malformations: Pathophysiology, Genetics, Biomarkers, and Treatment Perspectives

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Cerebral cavernous malformations (CCMs) are vascular lesions in the brain caused by inherited genetic mutations in the CCM1/2/3 genes that disrupt normal blood vessel function. This work demonstrates that these mutations lead to endothelial dysfunction, inflammation, and iron accumulation, which can be detected by magnetic resonance imaging (MRI) and ...
Fabrícia Lima Fontes‐Dantas, Gustavo da Fontoura Galvão, Alexandre Martins Cunha, Pedro de Sena Murteira Pinheiro, Verônica Morandi, Jorge Marcondes de Souza   +5 more
wiley   +1 more source

A review on fueling recovery: the role of metabolic modulation in non-obstructive myocardial stunning. [PDF]

Eur J Med Res
Özkan U, Yalta K, Gürdoğan M, Kounis NG, Altay S.   +4 more
europepmc   +1 more source

Somatostatin induces translocation of the beta-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells.

, 1987
Federico Mayor, Jeffrey Benovic, M G Caron, R J Lefkowitz   +3 more
openalex   +1 more source

Neurons in a Dish: A Review of In Vitro Cell Models for Studying Neurogenesis

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Different in vitro cell models are valuable to study the different steps of neurogenesis, from the proliferation of neural stem and progenitor cells to the maturation of neurons. Pluripotent stem cells (including embryonic stem cells and induced pluripotent stem cells), immortalized human neuroblastoma cell lines (SH‐SY5Y, IMR‐32), and primary brain ...
Mariana Vassal, Ana C. Cruz, Sandra Rebelo, Filipa Martins   +3 more
wiley   +1 more source

Neuro-tumor interactions: Multi-dimensional mechanisms of neurotransmitter regulation in tumor immune evasion and metabolic reprogramming. [PDF]

World J Clin Oncol
Li ZK, Liao JL, Luo MR, Fang SJ, Huang WZ, Zhang DY.   +5 more
europepmc   +1 more source

Therapeutic Potential of Melatonin in Gastrointestinal Cancers: Molecular Mechanisms, Preclinical Evidence and Clinical Implications

Journal of Pineal Research, Volume 78, Issue 1, January 2026.
ABSTRACT Gastrointestinal (GI) cancers remain a leading cause of global morbidity and mortality, necessitating novel therapeutic strategies. Melatonin (MEL), an indoleamine with pleiotropic biological activities, has emerged as a promising adjuvant in oncology due to its antiproliferative, proapoptotic, and antioxidant properties.
Maciej Gonciarz, Benita Wiatrak, Iga Lombard, Łukasz Konecki, Joanna Sarbinowska   +4 more
wiley   +1 more source