Cyclic nucleotide signaling as a drug target in retinitis pigmentosa. [PDF]
Vainionpää K, Montaser AB, Leinonen H.
europepmc +1 more source
Objective This study investigated the antiobesity effects of nicotiflorin, a flavonol glycoside structurally related to rutin, by examining its ability to activate brown adipose tissue (BAT) through the β3–adrenergic receptor (β3‐AR) pathway in mice with high‐fat diet (HFD)–induced obesity.
Chun-Yen Chiu +7 more
wiley +1 more source
β<sub>2</sub>-Adrenergic Receptor Agonists in Diabetic Kidney Disease: Exploring a New Frontier. [PDF]
Hegde S +4 more
europepmc +1 more source
The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira +2 more
wiley +1 more source
GPCR kinases phosphorylate GPCR C-terminal peptides in a hierarchical manner. [PDF]
Löbbert A +5 more
europepmc +1 more source
Multicomplex Pharmacophore Modeling of Estrogen Receptors Suggests the Probable Repurposing of Procaterol as an Antiproliferative Agent Against Breast Cancer Cells. [PDF]
Vazquez-Mendoza LH +6 more
europepmc +1 more source
Takotsubo Syndrome in 2025: Evolving Concepts in Pathophysiology, Diagnosis, and Long-Term Management. [PDF]
McKenzie A, Bargout R.
europepmc +1 more source
The beta1-adrenergic receptor in the heart. [PDF]
Xu W +8 more
europepmc +1 more source
Targetable pathways for drug repurposing in gastric cancer. [PDF]
Valero-Almingol A +10 more
europepmc +1 more source

