Results 201 to 210 of about 28,675 (270)

Nicotiflorin Alleviates Obesity by Activating Brown Adipose Tissue Through the β3–Adrenergic Receptor Pathway

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Objective This study investigated the antiobesity effects of nicotiflorin, a flavonol glycoside structurally related to rutin, by examining its ability to activate brown adipose tissue (BAT) through the β3–adrenergic receptor (β3‐AR) pathway in mice with high‐fat diet (HFD)–induced obesity.
Chun-Yen Chiu   +7 more
wiley   +1 more source

The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease

open access: yesJournal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira   +2 more
wiley   +1 more source

GPCR kinases phosphorylate GPCR C-terminal peptides in a hierarchical manner. [PDF]

open access: yesCommun Biol
Löbbert A   +5 more
europepmc   +1 more source

Multicomplex Pharmacophore Modeling of Estrogen Receptors Suggests the Probable Repurposing of Procaterol as an Antiproliferative Agent Against Breast Cancer Cells. [PDF]

open access: yesInt J Mol Sci
Vazquez-Mendoza LH   +6 more
europepmc   +1 more source

The beta1-adrenergic receptor in the heart. [PDF]

open access: yesCell Death Discov
Xu W   +8 more
europepmc   +1 more source

Targetable pathways for drug repurposing in gastric cancer. [PDF]

open access: yesWorld J Gastroenterol
Valero-Almingol A   +10 more
europepmc   +1 more source

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