Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Sports foods and dietary supplements for optimal function and performance enhancement in track and field athletes [PDF]
Numerous nutritional products are marketed with claims of optimizing athlete health and function and/or enhancing performance. Products that fall under the banner of “Sports Foods” or “Dietary Supplements,” may be used to support performance during ...
Peeling, Peter +4 more
core +1 more source
New Strategies in Sport Nutrition to Increase Exercise Performance. [PDF]
Despite over 50 years of research, the field of sports nutrition continues to grow at a rapid rate. Whilst the traditional research focus was one that centred on strategies to maximize competition performance, emerging data in the last decade has ...
A. Philp +191 more
core +1 more source
A carnosina diminui os efeitos da acidose muscular durante o exercício
A carnosina é um dipeptídeo composto pelos aminoácidos beta-alanina e histidina encontrado em maior parte no tecido muscular. Sua síntese ocorre através da enzima carnosina sintase tendo a beta alanina como precursor limitante. Estudos tem mostrado que o
Victor Araújo Ferreira Matos +5 more
doaj
Cellular and Physiological Effects of Dietary Supplementation with β-Hydroxy-β-Methylbutyrate (HMB) and β-Alanine in Late Middle-Aged Mice. [PDF]
There is growing evidence that severe decline of skeletal muscle mass and function with age may be mitigated by exercise and dietary supplementation with protein and amino acid ingredient technologies.
Julian Vallejo +6 more
doaj +1 more source
Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew +11 more
wiley +1 more source
Effect of β-alanine supplementation on 20 km cycling time trial performance [PDF]
The effects of β-alanine supplementation on high-intensity cycling performance and capacity have been evaluated, although the effects on longer duration cycling performance are unclear.
Artioli GG +31 more
core +5 more sources
Acute Supplementation with Beta-Alanine Improves Performance in Aerobic-Anaerobic Transition Zones in Endurance Athletes [PDF]
Álvaro Huerta Ojeda +5 more
openalex +1 more source
Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham +9 more
wiley +1 more source
Efeito da suplementação de beta-alanina no desempenho: uma revisão crítica
A beta-alanina é um aminoácido não proteogênico precursor limitante da síntese da carnosina. O aumento da carnosina muscular tem sido considerado um fator de reforço das capacidades físicas e diminuição da fadiga neuromuscular.
Bruna Amorim Zandoná +4 more
doaj

