Results 61 to 70 of about 913,637 (282)

Distribusi Gabungan Beta-Binomial Negatif [PDF]

, 2013
Skripsi ini membahas tentang pembentukan distribusi peluang gabungan antara distribusi Binomial Negatif dengan distribusi Beta. Distribusi peluang sangat berperan penting dalam menaksir peluang terjadinya klaim asuransi dengan terlebih dahulu menentukan ...
Fakih, BiastadiasSabirina
core  

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Beta-binomial distribution.

, 2023
β-binomial distributions for identical mean: μ, μ1 = 12 but different standard deviations: σ = 3, σ1 = 5. The dotted lines signifies the mean of the distribution where as the shaded area is the standard deviation across 5 trials. (PNG)
François-Xavier Dupé (17364494), Rohit Yadav (8206536), Guillaume Auzias (616230), Sylvain Takerkart (5659873)   +3 more
core   +1 more source

Improving analysis of cognitive outcomes in cardiovascular trials using different statistical approaches

Trials
Background The Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) questionnaires are commonly used to measure global cognition in clinical trials. Because these scales are discrete and bounded with ceiling and floor effects
Shun Fu Lee, William Whiteley, Jackie Bosch, Laura Sherlock, Tali Cukierman-Yaffe, Martin O’Donnell, John W. Eikelboom, Hertzel C. Gerstein, Shrikant I. Bangdiwala, Graciela Muniz-Terrera   +9 more
doaj   +1 more source

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

Advanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng, Jaegeon Joo, Yu Meng Li, Cheng Ji Li, Ali Taghizadeh, Seung Jae Shin, Buuvee Bayarkhangai, Tae‐Woo Ha, Sak Lee, Jaewoo Chung, Bo‐Eun Yoon, Hye Sung Kim, Inkyung Jung, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +15 more
wiley   +1 more source

Boosted beta regression. [PDF]

PLoS ONE, 2013
Regression analysis with a bounded outcome is a common problem in applied statistics. Typical examples include regression models for percentage outcomes and the analysis of ratings that are measured on a bounded scale.
Matthias Schmid, Florian Wickler, Kelly O Maloney, Richard Mitchell, Nora Fenske, Andreas Mayr   +5 more
doaj   +1 more source

Molecular Atlas of Key Food Odorants Reveals Mixture‐Level Organization and Enables Generative Aroma Design

Advanced Science, EarlyView.
KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang, Huadong Xing, Antonella Di Pizio, Qinfei Ke, Xingran Kou, Dachuan Zhang   +5 more
wiley   +1 more source

Comparison of the accuracy of beta-binomial, multinomial, dirichlet-multinomial, and ordinal regression in modelling quality of life data

Journal of Biostatistics and Epidemiology, 2018
Background & Aim: Questionnaires are used mostly as a tool in medical research. Due to the different varieties of questionnaires, we may face different score distributions. In many cases multiple linear regression assumptions are violated.
Ali Ghanbari, Mir Saeed Yekaninejad, Amir Pakpour, Sobhan Sanjari, Keramat Nourijelyani   +4 more
doaj  

scGEN: Leveraging an Adaptive Weighting Strategy for Challenging Cell Clustering in Single‐Cell RNA‐seq

Advanced Science, EarlyView.
scGEN combines attribute–structure encoding, adaptive hard‐sample weighting, and regularized zero‐inflated negative binomial loss to resolve ambiguous single‐cell states. In the developing human pituitary, refined annotations reveal Pre.Gonado cells at 7 weeks and previously obscured developmental communication networks.
Fang Huang, Dayu Hu, Yaqi Dai, Aoyi Geng, Renxiang Guan, Hao Quan, Brett A. McGregor, Zhihan Wang, Nadeem Khan, Hongsheng Zhang, Jinghua Zhang, Mingyang Xia, Xiaoqiong Gu, Di Che, Junguk Hur, Xiaoyu Cui, Kai Guo   +16 more
wiley   +1 more source