Results 41 to 50 of about 5,240,370 (291)
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl +6 more
wiley +1 more source
Multivariate beta binomial distribution model as a web media exposure model [PDF]
, 2007 This study develops and tests a new multivariate distribution model for the estimation of advertising vehicle exposure. The new multivariate distribution model is developed as three versions (i.e., one which doesn't adjust negative probabilities,
Cheong, Yunjae, 1976-
core +3 more sources
Acta Scientiarum. Agronomy, 2018 We investigated regression models with mixed effects using generalized linear statistics to evaluate germination data from Stevia rebaudiana (Bert) Bertoni.
Edilenia Queiroz Pereira +3 more
doaj +1 more source
Application of the Beta-Binomial Distribution for Statistical Processing of Student Grades [PDF]
Baikal Research Journal, 2020 Statistical processing of students' grades is used to solve various problems in managing the educational process. Traditional methods of mathematical statistics do not correspond to the properties of student grades. The paper proposes to adapt the IRT models for describing grades to improve the whole process. A model based on beta-binomial distribution
openaire +1 more source
Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph +5 more
wiley +1 more source
Limiting the Risk of the Bayes Estimator for the Binomial Distribution [PDF]
The Egyptian Statistical Journal, 1991 This article considers the Bayesian problem of estimating the probability of success θ of a binominal distribution when θ itself has a beta prior.
Reda Mazloum
doaj +1 more source
Mathematics, 2023 In this paper, we study a new type of distribution that generalizes distributions from the gamma and beta classes that are widely used in applications.
Alexey Kudryavtsev, Oleg Shestakov
doaj +1 more source