Results 51 to 60 of about 621,021 (292)
Animals, 2022 Of the diversity of proteins and high digestibility, goat milk will be a food of significant value for infant nutrition. The genetic polymorphisms of milk proteins play an essential role in the different degrees of allergic reactions.
Florencia Muñoz-Salinas +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Effect of the Genotypes of the CSN2 Gene on Test-Day Milk Yields in the Slovak Holstein Cow
Agriculture, 2023 The aim of this study was to analyze the polymorphisms of the beta-casein gene and describe the association between the beta-casein genotypes and milk production in high milk-production Slovak Holstein cattle herds. Genomic DNA was isolated from the hair
Martina Miluchová +2 more
doaj +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Pesquisa Agropecuária Brasileira, 2008 The objective of this work was to evaluate the effect of somatic cell counts (SCC) in casein fractions of ultra high temperature (UHT) milk. Raw milks were categorized in SCC groups of low (200,000-320,000 cells mL-1), intermediate (380,000-560,000 cells
Andrezza Maria Fernandes +5 more
doaj +1 more source
Advanced Science, EarlyView.Tightly focused laser irradiation can accumulate tubulin proteins at/around the laser focus, which leads to the formation of highly ordered microtubule assemblies. The assemblies can exhibit various dynamic behaviors such as radial motion, bundling, and flagella‐like rotation with motor protein and chemical energy, highlighting as a unique tool for ...
Hiroshi Y. Yoshikawa +16 more
wiley +1 more source
Milk protein and cheese yield in buffalo species
Italian Journal of Animal Science, 2010 Buffalo milk samples differing significantly for cheese yield values were analysed by 2D electrophoresis in order to outline a protein profile, with specific regards to k-casein fractions.
Rossella Di Palo +6 more
doaj +1 more source
Milk protein polymorphisms and effect of herds on cows` milk composition [PDF]
Journal of Central European Agriculture, 2013 Kappa-casein (CSN3) and beta-lactoglobulin (LGB) loci affect milk yield traits and the quality of milk protein. Their polymorphisms explain the role of genetic variance and facilitate estimation of breeding value. Our research was aimed at estimating the
Beata SITKOWSKA +4 more
doaj +1 more source
CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction
Advanced Science, EarlyView.CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma +12 more
wiley +1 more source
Czech Journal of Animal Science, 2020 The present study aimed to test the possibility of avoiding expensive retesting of the whole parental generation for single nucleotide polymorphisms (SNPs), to provide additional analysis of microsatellites in offspring in the transitional period and to ...
Michaela Přibáňová +6 more
doaj +1 more source