Results 111 to 120 of about 674,582 (266)
Beta-catenin (CTNNB1) plays a dual role in the cell, functioning both in cell adhesion and WNT signalling. In cell adhesion, CTNNB1 binds to cadherins in adherens junctions and anchors them to the cytoskeleton. This is crucial for reinforcing cell-cell junctions and maintaining structural integrity.
openaire +1 more source
Advanced Science, EarlyView.Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang +10 more
wiley +1 more source
Molecular and cellular pathogenesis of adamantinomatous craniopharyngioma
, 2015 Adamantinomatous craniopharyngiomas (ACPs) are the most common pituitary tumours in children. Although histologically benign, these are clinically aggressive tumours, difficult to manage and associated with poor quality of life for the patients.
Martinez-Barbera, JP
core
Annals of Gastroenterological Surgery, EarlyView.In this retrospective cohort of 3487 patients with CRC, history of CCY was associated with significantly worse prognosis in patients with proximal CRC but not in those with distal CRC. This differential prognostic impact showed a statistically significant interaction between tumor location and history of CCY and remained robust after PSM.
Masashi Tsunematsu +9 more
wiley +1 more source
Nuclear translocation of beta catenin in patients with Rathke cleft cysts-clinical and imaging characteristics and risk of recurrence. [PDF]
Acta Neurochir (Wien), 2023 Schmutzer M +6 more
europepmc +1 more source
, 2011 Background: Pulmonary sclerosing haemangioma (PSH) is an uncommon tumour that is composed of glandular/ papillary lining cells and polygonal cells. The biological behaviour of this tumour has been investigated; however, the molecular pathogenesis of PSH ...
江伯敏;袁瑞晃;許輝吉;毛翠蓮;胡瑞恆;賴寶蓮;鄭永銘 +1 more
core
Production of recombinant human beta-catenin protein in Ecoli and screening for anti-beta-catenin
, 2016 Cataloged from PDF version of article.
openaire +1 more source
Advanced Intelligent Discovery, EarlyView.This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
The VAX2-SERPINE1 axis modulates colorectal cancer cell proliferation and apoptosis through WNT/beta-catenin signaling. [PDF]
Transl OncolZhang J +18 more
europepmc +1 more source
Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley +1 more source