Results 151 to 160 of about 86,249 (262)

Correction: Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis. [PDF]

Oncotarget, 2023
Leal LF, Bueno AC, Gomes DC, Abduch R, de Castro M, Antonini SR.   +5 more
europepmc   +1 more source

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

In Vivo Efficacy of a Macrocyclic Peptoid-Peptide Hybrid That Selectively Modulates the Beta-Catenin/TCF Interaction to Inhibit Prostate Cancer. [PDF]

Prostate
Habault J, Franco JL, Ha S, Schneider JA, Voisin M, Wise DR, Wong KK, Garabedian MJ, Kirshenbaum K, Logan SK.   +9 more
europepmc   +1 more source

Phosphorylation-Dependent Regulation of WNT/Beta-Catenin Signaling. [PDF]

Front Oncol, 2022
Shah K, Kazi JU.
europepmc   +1 more source

Beta-catenin is an immune regulator.

Loss of function analysis demonstrated the tumor suppressor-like molecule has a dominant function in fine control of self non-self through activation of tissue-restricted antigens, most likely to restrict metastasis to distant organ sites. 
openaire   +3 more sources

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

Animal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang, Xuepei Lei, Yiying Huang, Jiaming Tang, Guiying Shi, Hang Li, Lin Bai   +6 more
wiley   +1 more source

SYS-1/beta-catenin inheritance and regulation by Wnt signaling during asymmetric cell division. [PDF]

Mol Biol Cell
Michel MFV, Phillips BT.
europepmc   +1 more source

Genome‐wide network analysis identifies the lncRNA‐92467/miR‐205‐5p/PTPRM/CAMs axis in a rat model of hypoxic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen, Yi‐Bing Chen, Xin Li, Xiang Xu, Ge Guo, Han‐Lu Li, Yong‐Ming Yao, Chun‐Lei Liu   +7 more
wiley   +1 more source

Evaluation of Immunohistochemical Expression of Beta-catenin and E-cadherin as Epithelial-Mesenchymal Transition Markers in Colorectal Carcinoma - An Analytical Retrospective Study in a Tertiary Care Center. [PDF]

Int J Appl Basic Med Res
Katta R, Nugala S, Kolakonda M, Chinnam A.   +3 more
europepmc   +1 more source

Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis. [PDF]

Nat Commun, 2023
Ding D, Blee AM, Zhang J, Pan Y, Becker NA, Maher LJ, Jimenez R, Wang L, Huang H.   +8 more
europepmc   +1 more source