Results 271 to 280 of about 1,125,892 (364)

Inhibition of cell growth by a beta-catenin responsive element

, 2003
Hadas Dvory‐Sobol, Talia Kunik, Dina Kazanov, Olga Kolker, Meirav Rozenblat, Efrat Cohen-Noyman, Ludmila Strier, Nadir Arber   +7 more
openalex   +1 more source

ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids

Advanced Science, EarlyView.
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin, Yulong Hong, Yongqi Zhao, Wensheng Shi, Ruilin Liu, Xinyu You, Chong Yang, Yu Zhang   +7 more
wiley   +1 more source

Expression of β-catenin in colorectal polyps

, 2003
Tomoaki Hatakeyama, Jun Takatsuka, Kousuke Okamoto, Hideyuki KOSINO, S. Hamatani, Tadaaki SHIBA   +5 more
openalex   +2 more sources

ROS‐Responsive Hydrogel for Localized Delivery of Nampt and Stat3 Inhibitors Exhibits Synergistic Antitumor Effects in Colorectal Cancer Through Ferroptosis Induction and Immune Microenvironment Remodeling

Advanced Science, EarlyView.
In this study, ferroptosis in colorectal cancer cells is induced by FK866 through the NAD⁺/STAT3/GPX4 pathway. To minimize systemic toxicity, a reactive oxygen species (ROS)‐responsive hydrogel is developed to co‐deliver FK866 and C188‐9, resulting in synergistic and localized antitumor effects.
Chenyang Ye, Mi Mi, Saimeng Shi, Lina Qi, Shanshan Weng, Lu Wang, Yier Lu, Chao Chen, Yinuo Tan, Mengyuan Yang, Cheng Guo, Rui Bai, Xuefeng Fang, Ji Wang, Ying Yuan   +14 more
wiley   +1 more source

Comparative immunohistochemical expression of Beta catenin and CD163 between dysplastic / non-dysplastic oral lichen planus and lichenoid lesions (EX-VIVO STUDY). [PDF]

BMC Oral Health
Saleh HA, Nabil G, Badawy SAMM.
europepmc   +1 more source

Faculty Opinions recommendation of Role of beta-catenin in synaptic vesicle localization and presynaptic assembly.

, 2003
Randall T. Moon
openalex   +2 more sources

beta-catenin independent WNT signaling

Reactome - a curated knowledgebase of biological pathways, 2014
openaire   +2 more sources

RUNX1/SLAMF3 Axis Drives Immunosuppression to Contribute to Colorectal Cancer Liver Metastasis by Blocking Phagocytosis and Depleting C1QC+ Tumor‐Associated Macrophages

Advanced Science, EarlyView.
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo, Xiaoli Jin, Lan Huang, Dejia Zeng, Nan Zhang, Shiyu Tang, Shu Luo, Samina Ejaz Syed, Ruiwu Dai, Qiu Li, Shufang Liang   +10 more
wiley   +1 more source

Faculty Opinions recommendation of Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity.

, 2005
Scott A. Holley
openalex   +3 more sources

YAP/TAZ, beta-catenin, and TGFb pathway activation in medical plasma-induced wound healing in diabetic mice. [PDF]

J Adv Res
Schmidt A, von Woedtke T, Weltmann KD, Bekeschus S.   +3 more
europepmc   +1 more source