Results 281 to 290 of about 1,106,914 (319)

miR-185 suppresses progression of Ewing’s sarcoma via inhibiting the PI3K/AKT and Wnt/β-catenin pathways

, 2018
Sam Zhang, Li D, Guangjun Jiao, Hong Wang, Tao Yan   +4 more
openalex   +1 more source

Downregulation of MMSET impairs breast cancer proliferation and metastasis through inhibiting Wnt/β-catenin signaling

, 2019
X Zhao, Tian Xie, W-H Zhao, Weimin Cai, Xinhui Su   +4 more
openalex   +1 more source

Raab MS, Breitkreutz I, Tonon G, et al. Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling. Blood. 2009;113(7):1513-1521.

Blood
europepmc   +1 more source

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Adenoid ameloblastoma harbors beta-catenin mutations

Modern Pathology, 2022
Adenoid ameloblastoma is a very rare benign epithelial odontogenic tumor characterized microscopically by epithelium resembling conventional ameloblastoma, with additional duct-like structures, epithelial whorls, and cribriform architecture. Dentinoid deposits, clusters of clear cells, and ghost-cell keratinization may also be present.
Victor Coutinho Bastos, Bruna Pizziolo Coura, Letícia Martins Guimarães, Bianca Gomes Fernandes, Alexander Chak-Lam Chan, Pablo Agustin Vargas, Luciana Bastos-Rodrigues, Luiz Armando De Marco, John Hellstein, Selvam Thavaraj, John M. Wright, Edward William Odell, Ricardo Santiago Gomez, Carolina Cavaliéri Gomes   +13 more
openaire   +3 more sources

beta-catenin expression in pilomatrixomas. Relationship with beta-catenin gene mutations and comparison with beta-catenin expression in normal hair follicles

British Journal of Dermatology, 2001
beta-catenin functions in signal transduction in the Wnt signalling pathway, which has recently been implicated in hair follicle (HF) morphogenesis. beta-catenin gene mutations affecting exon 3 have been reported in a high percentage of human pilomatrixomas.
G, Moreno-Bueno, C, Gamallo, L, Pérez-Gallego, F, Contreras, J, Palacios   +4 more
openaire   +2 more sources

Wnt/beta-Catenin Signaling in Glioma

Journal of Neuroimmune Pharmacology, 2012
Extensive data have shown that Wnt/beta-catenin signaling is associated with various disease pathologies, including an important role in tumorigenesis. Here, we review the regulation of Wnt/beta-catenin signaling in glioma, with particular focus on the expression signatures of the main components in Wnt/beta-catenin signaling, the role of key factors ...
Kailiang, Zhang, Junxia, Zhang, Lei, Han, Peiyu, Pu, Chunsheng, Kang   +4 more
openaire   +2 more sources

p35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction

European Journal of Neuroscience, 2001
The neuronal cyclin-dependent kinase p35/cdk5 comprises a catalytic subunit (cdk5) and an activator subunit (p35). To identify novel p35/cdk5 substrates, we utilized the yeast two-hybrid system to screen for human p35 binding partners. From one such screen, we identified beta-catenin as an interacting protein.
Kesavapany, S, Lau, K F, McLoughlin, D M, Brownlees, J, Ackerley, S, Leigh, P N, Shaw, C E, Miller, C C J   +7 more
openaire   +3 more sources

The WNT/Beta-catenin pathway in melanoma

Frontiers in Bioscience, 2006
The Wnt/beta-catenin pathway is involved in various cellular activities--including determination, proliferation, migration and differentiation--in embryonic development and adult homeostasis. The deregulation or constitutive activation of the Wnt/beta-catenin pathway may lead to cancer formation.
Lionel, Larue, Véronique, Delmas
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beta-catenin-cell adhesion and beyond (review)

International Journal of Oncology, 1997
beta-catenin was originally identified as a cytosolic cell protein required for the correct function of the cadherin cell-cell adhesion complex. However, recent studies have identified the presence of intracellular pools of beta-catenin that are cadherin-independent and that beta-catenin is also involved in Wnt-1, src and Tcf-Lef mediated intracellular
W, Jiang, S, Hiscox
openaire   +2 more sources