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Raab MS, Breitkreutz I, Tonon G, et al. Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling. Blood. 2009;113(7):1513-1521.

Blood
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Wnt/beta-Catenin Signaling in Glioma

Journal of NeuroImmune Pharmacology, 2012
Extensive data have shown that Wnt/beta-catenin signaling is associated with various disease pathologies, including an important role in tumorigenesis. Here, we review the regulation of Wnt/beta-catenin signaling in glioma, with particular focus on the expression signatures of the main components in Wnt/beta-catenin signaling, the role of key factors ...
Chunsheng Kang
exaly   +4 more sources

The WNT/Beta-catenin pathway in melanoma

Frontiers in Bioscience - Landmark, 2006
The Wnt/beta-catenin pathway is involved in various cellular activities--including determination, proliferation, migration and differentiation--in embryonic development and adult homeostasis. The deregulation or constitutive activation of the Wnt/beta-catenin pathway may lead to cancer formation.
Lionel Larue, Véronique Delmas
exaly   +4 more sources

In melanoma, beta-catenin is a suppressor of invasion [PDF]

Oncogene, 2011
Cell-type-specific signalling determines cell fate under physiological conditions, but it is increasingly apparent that also in cancer development the impact of any given oncogenic pathway on the individual cancer pathology is dependent on cell-lineage-specific molecular traits.
Arozarena, I, Bischof, H, Gilby, D, Belloni, B, Dummer, R, Wellbrock, C   +5 more
exaly   +4 more sources

Beta-catenin-activated hepatocellular adenoma in a male

Clinical Journal of Gastroenterology, 2021
Beta-catenin-activated hepatocellular adenoma is potentially malignant and warrants careful follow-up and surgical resection. Here, we report a 48-year-old man in whom a 55 mm single liver tumor was incidentally detected in the S1 segment. Contrast-enhanced computed tomography scans showed no enhancement in the early phase and a slight defection in the
Ryosuke Ishida, Yoshihiko Yano, Atsushi Yamamoto, Eiichiro Yasutomi, Yuri Hatazawa, Hiroki Hayashi, Yuuki Shiomi, Hidetoshi Gon, Satoshi Omiya, Maki Kanzawa, Tomoo Itoh, Yoshihide Ueda, Yuzo Kodama   +12 more
openaire   +3 more sources

beta-catenin expression in pilomatrixomas. Relationship with beta-catenin gene mutations and comparison with beta-catenin expression in normal hair follicles

British Journal of Dermatology, 2001
beta-catenin functions in signal transduction in the Wnt signalling pathway, which has recently been implicated in hair follicle (HF) morphogenesis. beta-catenin gene mutations affecting exon 3 have been reported in a high percentage of human pilomatrixomas.
C Gamallo, J Palacios, Gema Moreno-Bueno, L Pérez-Gallego, F Contreras   +4 more
openaire   +3 more sources

Beta-Catenin and the Survival of Hepatocytes

2017
The Wnt/β-catenin pathway is critical for liver development, differentiation, metabolism, and homeostasis. Aberrations in this pathway have also been identified in many pathophysiological conditions, such as nonalcoholic steatohepatitis, fibrosis, and hepatobiliary neoplasias.
Kari Nejak-Bowen, Satdarshan P.S. Monga
openaire   +2 more sources