Results 311 to 320 of about 119,479 (336)

Characterization of a BETA-Catenin-Associated Kinase

1999
Abstract : Several lines of evidence suggest that accumulation of cytoplasmic Beta-catenin transduces an oncogenic signal. We show that Beta-cantenin is ubiquitinated and degraded by the proteosome and that Beta-cantenin stability is regulated by a diacylglycerol-independent protein kinase C-like kinase activity which is required for Beta-catenin ...
openaire   +1 more source

Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription.

Cancer research, 2001
Beta-catenin undergoes both serine and tyrosine phosphorylation. Serine phosphorylation in the amino terminus targets beta-catenin for proteasome degradation, whereas tyrosine phosphorylation in the COOH terminus influences interaction with E-cadherin.
BONVINI P., AN W. G., ROSOLEN, ANGELO, NGUYEN P., TREPEL J., GARCIA DE HERREROS A., DUNACH M., NECKERS L. M.   +7 more
openaire   +2 more sources

Beta Catenin-Regulated Genes in Breast Cancer [PDF]

, 1999
Abstract : This study investigates the role of cadherin-11 in the progression of breast cancer from a less invasive, more differentiated phenotype to a more invasive, less differentiated phenotype. The cadherins are transmembrane proteins that have been shown in many previous studies to be involved in cancer progression.
openaire   +1 more source

Expression of beta-catenin in human tooth germ.

Analytical and quantitative cytology and histology, 2009
To evaluate beta-catenin expression in human tooth germ development.Specimens of 7 human fetuses aged between the ninth and sixteenth week were examined for beta-catenin expression by immunohistochemistry.In the bud stage, we observed catenin membranous positivity for all primitive dental lamina and dental ridge cells, cytoplasmic positivity for tooth ...
LO MUZIO L, LO RUSSO L, PANNONE G, SANTORO A, LEONARDI R, SERPICO, Rosario, GASPARONI A, BUFO P.   +7 more
openaire   +2 more sources

Beta-Catenin

2012
Ken-Ichi Takemaru, Xingwang Chen, Feng-Qian Li   +2 more
openaire   +1 more source

A role for alpha-and beta-catenins in bacterial uptake.

Proceedings of the National Academy of Sciences of the United States of America, 2000
Interaction of internalin with E-cadherin promotes entry of Listeria monocytogenes into human epithelial cells. This process requires actin cytoskeleton rearrangements. Here we show, by using a series of stably transfected cell lines expressing E-cadherin variants, that the ectodomain of E-cadherin is sufficient for bacterial adherence and that the ...
Lecuit, Marc, Hurme, Reini, Pizarro-Cerdá, Javier, Ohayon, Hélène, Geiger, Benjamin, Cossart, Pascale   +5 more
openaire   +3 more sources

Pathogenetic Analysis of Sinonasal Teratocarcinosarcomas Reveal Beta-catenin Overexpression and an Actionable Beta-catenin Mutation

Journal of Neurological Surgery Part B: Skull Base, 2016
Chad Brenner, Erin L. McKean, Jacques E. Nör, Sarah J. Burgin, Andrew C. Birkeland, Scott A. McLean, Jonathan B. McHugh   +6 more
openaire   +2 more sources

Beta-Catenin in Squamous Cell Carcinoma

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2005
S.C.O.M. Sousa, D.S. Pinto, Fábio Daumas Nunes   +2 more
openaire   +2 more sources

Immunohistochemical analysis of beta-catenin, E-cadherin and p53 in canine gastrointestinal epithelial tumors

Journal of Veterinary Medical Science, 2020
James Chambers, Koichi Ohno, Hajime Tsujimoto   +2 more
exaly  

Circadian rhythms, Wnt/beta-catenin pathway and PPAR alpha/gamma profiles in diseases with primary or secondary cardiac dysfunction

Frontiers in Physiology, 2014
Yves Lecarpentier, Jean-louis Hébert
exaly