Results 1 to 10 of about 2,508 (166)
beta-endorphin-(1-27) is an antagonist of beta-endorphin analgesia. [PDF]
Proceedings of the National Academy of Sciences, 1984 beta h-Endorphin-(1-27), a naturally occurring fragment of human beta-endorphin (beta h-endorphin), diminishes the analgesic effect of beta h-endorphin when coinjected intra-cerebroventricularly into mice. A parallel shift in the dose-response curve of beta h-endorphin in the presence of beta h-endorphin-(1-27) suggests competition at the same site ...
R. Glenn Hammonds +2 more
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beta-endorphin is a potent analgesic agent. [PDF]
Proceedings of the National Academy of Sciences, 1976 beta-Endorphin, an opiate-like peptide, has potent antinociceptive properties when it is administered directly into the brain and assayed in the the tail-flick, hot-plate, and writhing tests in mice and in the wet shake test in rats. On a molar basis, beta-endorphin is 18 to 33 times more potent than morphine and its actions are blocked by the specific
Horace H. Loh +3 more
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Biotransformation of beta-endorphin and possible therapeutic implications [PDF]
Frontiers in Pharmacology, 2014 Endogenous opioid peptides have been aligned with a diverse array of effects. Their activity is not only attributable to action the three main opioid receptors, mu (MOR), delta (DOR), and kappa (KOR) opioid receptors but their impacts appear to extend to activities at sodium channels, cytokine receptors (Finley et al., 2008), calcium channels and non ...
Naghmeh Hajarol Asvadi +4 more
doaj +5 more sources
The role of beta-endorphin in horses: a review [PDF]
Veterinární Medicína, 2011 Opium alkaloids counterparts are secreted by human and animal organisms but the role of endogenous opioid peptides in horses has not yet been fully elucidated.
M. Golynski, W. Krumrych, K. Lutnicki
doaj +3 more sources
Biomolecules, 2021 Physical exercise has wide-ranging benefits to cognitive functioning and mental state, effects very closely resembling enhancements to hippocampal functioning.
Timothy J. Schoenfeld, Chance Swanson
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2021 Endogenous opioids have been implicated in cocaine reward. However, the role of each opioid peptide in this regard is unknown. Notably, the role of each peptide in extinction and reinstatement is not fully characterized. Thus, we assessed whether cocaine-
Prableen K. Singh, Kabirullah Lutfy
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The Role of Beta-Endorphin in Food Deprivation-Mediated Increases in Food Intake and Binge-Eating
Brain Sciences, 2023 Food deprivation and binge eating represent significant public health concerns. Previous studies have implicated that hypothalamic opioids are affected following food deprivation.
Laica Tolentino +3 more
doaj +1 more source
AAV gene therapy vectors in the TMJ
Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1561-1566, December 2022., 2022 Abstract Objectives The goal of this project was to evaluate the use of two adeno‐associated viral vector serotypes, adeno‐associated viral vectors (AAV)‐2 and AAV‐6, approved for and used for gene therapy in humans, for the delivery of therapeutic genes to the temporomandibular joint (TMJ) and the attendant sensory nerves.
Sabine M. Brouxhon +2 more
wiley +1 more source
Depression and Anxiety, Volume 39, Issue 12, Page 922-931, December 2022., 2022 Abstract Background Ambulatory assessments offer opportunities to study physical activity level (PAL) and affect at the group and person‐level. We examined bidirectional associations between PAL and affect in a 3‐h timeframe and evaluated whether associations differ between people with and without current or remitted depression/anxiety.
Sonia Difrancesco +5 more
wiley +1 more source