Results 101 to 110 of about 25,666 (269)

Ketogenic diet therapy for children with super‐refractory status epilepticus in intensive care: International clinical practice recommendations

Epilepsia Open, EarlyView.
Abstract Objective We aimed to create practical recommendations to support healthcare teams starting ketogenic diet therapy (KDT) for children with super‐refractory status epilepticus in intensive care settings. Methods A literature review was conducted to extract published data on patient selection, diet prescription, diet initiation, monitoring, fine‐
Robyn Blackford, Victoria J. Whiteley, Isobel Hardy, Marisa Armeno, Tessa Bollard, J. Helen Cross, Christin Eltze, Susan George, Charlotte Howard, A. Laura Nijstad, Erin Talzzia, Chris Paget, Samiran Ray, Zoe Simpson, Elizabeth Song‐Pozderac, Agnieszka Szmurlo, Charlene Tan‐Smith, Lisa Vanatta, Elles van der Louw, Natasha E. Schoeler, on behalf of the Ketogenic Dietitians Research Network   +20 more
wiley   +1 more source

Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects

Frontiers in Nutrition
IntroductionThe brain uses ketones, mainly 3-hydroxybutyrate (3-HB), as an alternative energy source. Therefore, oral intake of 3-HB may help maintain brain health.
Kentaro Nishioka, Kentaro Nishioka, Kentaro Nishioka, Takahiro Ishimoto, Mariko Sato, Ruki Yasuda, Yumi Nakamura, Hiroshi Watanabe, Toshihide Suzuki, Yudai Araragi, Yukio Kato, Ken-ichi Yoshida, Norihito Murayama   +12 more
doaj   +1 more source

Metabolic footprinting of extracellular metabolites of brain endothelium infected with Neospora caninum in vitro [PDF]

, 2014
BACKGROUND: The survival of the intracellular protozoan parasite Neospora caninum depends on its ability to adapt to changing metabolic conditions of the host cell.
Hany M Elsheikha, Kenny Kong, Mamdowh Alkurashi, Xing-Quan Zhu   +3 more
core   +2 more sources

Children with Epilepsy With Different Baseline Blood Beta‐hydroxybutyrate Have Similar Blood Beta‐hydroxybutyrate and Response on Ketogenic Therapy

The FASEB Journal, 2015
Background Children with epilepsy may have fasting blood beta‐hydroxybutyrate (BOB) similar to (low BOB) or higher than (high BOB) healthy children, which could reflect differences in metabolism or usual diet. BOB increases in children with epilepsy on Ketogenic Therapy (KT), where fat is most of the Calories ...
Hannah Allen, Giselle Pacheco, Dylan Lennon, Jurate Lukosaityte, Peggy Borum   +4 more
openaire   +1 more source

2-Deoxyglucose and Beta-Hydroxybutyrate: Metabolic Agents for Seizure Control

Frontiers in Cellular Neuroscience, 2019
Current anti-seizure drugs (ASDs) are believed to reduce neuronal excitability through modulation of ion channels and transporters that regulate excitability at the synaptic level. While most patients with epilepsy respond to ASDs, many remain refractory
Jong M. Rho, Jong M. Rho, Jong M. Rho, Li-Rong Shao, Carl E. Stafstrom   +4 more
doaj   +1 more source

A Forward-Design Approach to Increase the Production of Poly-3-Hydroxybutyrate in Genetically Engineered Escherichia coli [PDF]

, 2015
Biopolymers, such as poly-3-hydroxybutyrate (P(3HB)) are produced as a carbon store in an array of organisms and exhibit characteristics which are similar to oil-derived plastics, yet have the added advantages of biodegradability and biocompatibility ...
Bower, I, Chi, W, Chin, MHW, Fan, S, Freemont, P, Jensen, K, Kelwick, R, Kitney, R, Kopniczky, M, Pilcher, J, Stan, G-B, Strutt, J, Webb, AJ   +12 more
core   +3 more sources

Integrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis

iMeta, EarlyView.
Liver cirrhosis is associated with profound disruption of host–microbiome metabolic interactions. Using paired oral and fecal metagenomics combined with genome‐scale metabolic modeling, we investigated how microbial translocation along the oral–gut axis influences microbial metabolism at different cirrhosis severities.
Yi Jin, Frederick Clasen, Fernando Garcia‐Guevara, Sania Arif, Robert Schierwagen, Gholamreza Bidkhori, Michael Praktiknjo, Maximilian J. Brol, Frank E. Uschner, Florence A. Castelli, Nicolas Pons, Benoit Quinquis, Nathalie Galleron, Kevin Da Silva, Christophe Junot, Debbie L. Shawcross, David L. Moyes, Rajiv Jalan, S. Dusko Ehrlich, Vishal C. Patel, Jonel Trebicka, Saeed Shoaie   +21 more
wiley   +1 more source

Ferulic acid‐impregnated sodium alginate–pectin biopolymer film for active packaging and shelf‐life extension of potato chips

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND This study explores the development of active films incorporating ferulic acid (FA), a natural antioxidant, at concentrations of 0 (F1), 2.5 (F2), and 5 g L−1 (F3) into sodium alginate (SA; 13 g kg−1) and pectin (P; 10 g kg−1) matrix.
Shaik Sadiya, Venkata Giridhar Poosarla, Navyasri Nandavarapu, Aparna Ramadoss, Nagaveni Shivshetty   +4 more
wiley   +1 more source

ADMINISTRATION OF EARLY POST-PARTUM ORAL DRENCH IN DAIRY COWS: EFFECTON METABOLIC PROFILE

Revista de la Facultad de Medicina Veterinaria y de Zootecnia, 2015
Some prophylactic treatments have been proposed in high-yielding dairy cattle in order to minimize the effects of negative energy balance and some disturbances such as hypocalcaemia and ketosis.
R. Schallenberger Gonçalves, F. Cardoso, F. de Souza Guagnini, L. J. Reyes Castañeda, F. Gonzalez   +4 more
doaj  

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source