Results 231 to 240 of about 591,181 (270)

Association of Beta Hydroxybutyric Acidosis with Isoniazid Intoxication

Journal of Toxicology: Clinical Toxicology, 1984
Acute metabolic acidosis associated with accumulation of lactate has been previously reported in isoniazid (INH) intoxication. To our knowledge, association of INH toxicity with beta-hydroxybutyric acidosis has not been demonstrated previously. The present report documents the occurrence of beta-hydroxybutyric acidosis in patients with INH intoxication.
M V, Pahl, N D, Vaziri, R, Ness, R, Nathan, M, Maksy   +4 more
openaire   +2 more sources

Influence of beta-hydroxybutyrate on cultured mammalian cells

Experimental Cell Research, 1965
Abstract Accumulation of fat granules in cultured human liver cells and mouse fibroblasts was induced by β-hydroxybutyrate (BHB) at concentrations of 1 per cent or more. Metabolic effects concomitant with the ketone produced accumulation of fat granules included reduced DNA synthesis and glucose utilization.
W B, Savchuck, W L, Lockhart, M E, Merriman   +2 more
openaire   +2 more sources

UNRECOGNIZED PERSISTENCE OF BETA-HYDROXYBUTYRATE IN DIABETIC KETOACIDOSIS

Endocrine Research, 2001
We quantitated serial serum beta-hydroxybutyrate (beta-OHB) levels using the Ketosite method in 9 children with IDDM who were treated for diabetic ketoacidosis (DKA) and compared them to urinary ketone measurements by dipstick. Persistent elevations of serum beta-OHB were seen in six patients when the urine became clear of ketones; five of these ...
U M, Nadgir, F L, Silver, M H, MacGillivray   +2 more
openaire   +2 more sources

Modulation of beta-hydroxybutyrate in traumatic brain injury

Current Opinion in Clinical Nutrition & Metabolic Care
Purpose of review Traumatic brain injury (TBI) is a significant public health concern with substantial morbidity and mortality rates in the United States. Current management strategies primarily focus on symptomatic approaches and prevention of secondary complications.
Niraj, Arora, Dhaval Hitendrakumar, Shastri, Utsav Prakashbhai, Patel, Kunal, Bhatia   +3 more
openaire   +2 more sources

Beta-Hydroxybutyrate: A Supplemental Molecule for Various Diseases

Current Drug Targets
: β-hydroxybutyrate (BHB) is a ketone body that serves as an alternative energy source for various tissues, including the brain, heart, and skeletal muscle. As a metabolic intermediate and signaling molecule, BHB plays a crucial role in modulating cellular and physiological processes.
Navid Reza Shahtaghi, Bindu Soni, Hossamaldeen Bakrey, Samira Bigdelitabar, Subheet Kumar Jain   +4 more
openaire   +2 more sources

Reversible modification of D-.beta.-hydroxybutyrate dehydrogenase by diamide

Biochemistry, 1984
D-beta-Hydroxybutyrate dehydrogenase is a lipid-requiring enzyme with a specific requirement of lecithin for function. The purified enzyme devoid of lipid (apodehydrogenase) is inactive but can be reactivated by forming a complex with phospholipid containing lecithin.
E A, Fleer, J O, McIntyre, S, Fleischer
openaire   +2 more sources

A spectrophotometric micro-method for the enzymatic determination of beta-hydroxybutyrate

Clinica Chimica Acta, 1972
Abstract A simple, spectrophotometric micro-method for the determination of D -β-hydro-xybutyrate is described. A study of the conditions of the reaction showed that the inclusion of hydrazine as an agent for trapping the acetoacetic acid formed in the reaction was obligatory. Product inhibition due to excess acetoacetate was noted in the absence of
A, Chandrasekaran, R J, Glover, P S, Lord   +2 more
openaire   +2 more sources

Capillary beta-hydroxybutyrate determination for monitoring diabetic ketoacidosis

Endocrinología y Nutrición (English Edition), 2011
Diabetic ketoacidosis (DKA) is the most severe acute metabolic complication of type 1 diabetes mellitus. Insulin treatment is commonly guided by plasma glucose levels and changes in venous blood gases, while β-hydroxibutyrate (BHB) levels are rarely measured.
Beatriz, Rodríguez-Merchán, Ana, Casteràs, Eva, Domingo, Francisco José, Nóvoa, Yaiza, López, José Manuel, Cabezas-Agricola, Teresa, Rivero, Mónica, Parramón, Jordi, Mesa   +8 more
openaire   +2 more sources

Effect of Beta‐hydroxybutyrate on Myoblast Proliferation and Differentiation

The FASEB Journal, 2019
Ketogenic diets (KDs) and fasting have been promoted for weight loss and health. KDs cause an increase in circulating levels of ketone bodies, including beta‐hydroxybutyrate (βHB). The effects of amplified levels of βHB on skeletal muscle proliferation and differentiation are largely unknown. Therefore, we tested whether βHB has an
Joshua R. Melanson, Zachary E Olsen, Chase M. Walton, Benjamin T. Bikman, David M. Thomson   +4 more
openaire   +1 more source

Postmortem Vitreous Beta‐Hydroxybutyrate: Interpretation in a Forensic Setting*

Journal of Forensic Sciences, 2012
Abstract:  Vitreous beta‐hydroxybutyrate (BHB) was retrospectively analyzed in 1795 forensic cases using the Pointe Scientific method. Comparison of vitreous BHB with vitreous glucose in 1781 of the cases showed moderately good correlation r = 0.731. Comparison with blood alcohol levels in 1561 of the cases showed no correlation r = −0.053.
openaire   +2 more sources