Beta-lactam resistance mechanisms in gram-negative bacteria [PDF]
Beta-lactam antibiotics are commonly used to treat a variety of bacterial infections. Gram-negative bacteria have evolved several resistance mechanisms including altered permeability and beta-lactamase production.
Cole, S T, Nicolas, M H
core
Impact of a Rapid Change in Beta-lactam Resistance Epidemiology on the Management of Patients With Bloodstream Infections. [PDF]
Bobbitt L +4 more
europepmc +1 more source
Mandatory linking of penicillin allergy "safety alert" with beta-lactam medication history: correcting the automated inaccuracy of penicillin allergy labeling and beta-lactam antibiotic avoidance. [PDF]
Olans RN, Witt DJ, Marfatia R, Olans RD.
europepmc +1 more source
Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane +12 more
wiley +1 more source
Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin
This study included 28 amoxicillin‐allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free amoxicillin or G4/G5‐AXO dendrimers with successfully activated ...
Jose A. Céspedes +11 more
wiley +1 more source
Beta-lactam plus macrolide treatment versus beta-lactam monotherapy for community-acquired pneumonia: a propensity score analysis using data from a multicenter prospective cohort study. [PDF]
Nakashima K +8 more
europepmc +1 more source
Carriage of antimicrobial‐resistant E. coli in urban stray cats (Felis catus)
Antimicrobial resistance (AMR) in Escherichia coli is a growing concern in both human and veterinary medicine, driven by the inappropriate use of antimicrobials. Companion animals may act as community reservoirs and sentinels for antimicrobial‐resistant bacteria due to their close contact with humans and other animals.
JS Kuan, S Mukerji, D Hampson, S Abraham
wiley +1 more source
Frequency and severity of systemic reactions during beta-lactam skin testing in adults with immediate hypersensitivity allergy. [PDF]
Letón-Cabanillas P +4 more
europepmc +1 more source
Diagnosis and management of neutropenia in adults: Expert guidance
Severe neutropenia can result from decreased production of neutrophil precursors in the bone marrow, as in the case of severe congenital neutropenia, or from increased utilization of neutrophils or their accelerated destruction as for drug‐induced neutropenia or autoimmune neutropenia. Severe chronic neutropenia increases susceptibility to bacterial or
Karl Welte +5 more
wiley +1 more source
Daptomycin failure in the treatment of Enterococcus faecium bacteremia: microbiological insights and the importance of dual therapy including beta-lactam. [PDF]
Luque Paz D, Tattevin P.
europepmc +1 more source

