Results 61 to 70 of about 92,512 (212)

Emergence and Genomic Characterization of a Hypervirulent Klebsiella pneumoniae Isolate From a New Clone in Brazil

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) has emerged globally as a major public health concern, often associated with severe community‐acquired and healthcare‐associated human infections. Despite alerts from PAHO/WHO on convergent hvKp strains with multidrug resistance in Latin America, comprehensive data from Brazil, the region's largest ...
Carlos Henrique Camargo   +21 more
wiley   +1 more source

Genome Sequence of AvianEscherichia coliStrain IHIT25637, an Extraintestinal PathogenicE. coliStrain of ST131 Encoding Colistin Resistance Determinant MCR-1 [PDF]

open access: yes, 2016
Sequence type 131 (ST131) is one of the predominant Escherichia coli lineages among extraintestinal pathogenic E. coli (ExPEC) that causes a variety of diseases in humans and animals and frequently shows multidrug resistance.
Bauerfeind, Rolf   +8 more
core   +2 more sources

Altered Pathogen Spectrum of Spontaneous Bacterial Peritonitis in Patients Treated With Proton Pump Inhibitors

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
This multicenter, observational study reveals distinct alterations in the microbial spectrum of spontaneous bacterial peritonitis (SBP) associated with proton pump inhibitor use. These results are especially relevant for guiding empiric antibiotic therapy of SBP.
Philip Kitchen   +13 more
wiley   +1 more source

Generation of equine‐specific local antibiograms: reproductive tract of mares and fillies in Western Australia

open access: yesAustralian Veterinary Journal, EarlyView.
Introduction Antimicrobial resistance (AMR) may lead to increasing inefficacy and treatment failure of bacterial infections in the future. Antimicrobial stewardship (AMS) programmes are critical to ensuring the continued efficacy of available antimicrobials.
JKH Hoong, C Boyd, C Secombe, D Byrne
wiley   +1 more source

Phylogeny, Resistome, and Virulome of Escherichia coli Causing Biliary Tract Infections [PDF]

open access: yes, 2019
Escherichia coli is the most frequent Gram-negative bacilli involved in intra-abdominal infections. However, despite high mortality rates associated with biliary tract infections due to E. coli, there is no study focusing on this pathogen. In this study,
Aznar Martín, Javier   +8 more
core   +2 more sources

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

open access: yesBJU International, EarlyView.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon   +3 more
wiley   +1 more source

Antibiotic susceptibility and high prevalence of extended spectrum beta-lactamase producing Escherichia coli in iranian broilers [PDF]

open access: yes, 2016
Extended-spectrum β-lactamase (ESBL) producing Escherichia coli have rapidly spread worldwide and cause serious threats for public health. The study was conducted to determine the antibiotic resistance and characterization of ESBL producing E.
Khoshbakht, R., Raeisi, M., Seifi, S.
core  

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Antibiotic prophylaxis is associated with subsequent resistant infections in children with an initial extended-spectrum-cephalosporin-resistant Enterobacteriaceae infection [PDF]

open access: yes, 2017
The objective of this study was to assess the association between previous antibiotic use, particularly long-term prophylaxis, and the occurrence of subsequent resistant infections in children with index infections due to extended-spectrum-cephalosporin ...
Adler, Amanda L   +12 more
core   +2 more sources

S1 Guideline on Infected Interdigital Intertrigo (also called Gram‐Negative Toe Web Infection)

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Infected interdigital intertrigo is an exudative, macerating, mixed infection of the toe webs in which gram‐negative bacteria (Pseudomonas aeruginosa and Enterobacterales) seem prevalent, but in which gram‐positive pathogens (Staphylococcus [S.] aureus, streptococci, enterococci) and fungi (dermatophytes, yeasts) also occur.
Christoph Zeyen   +10 more
wiley   +1 more source

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