Results 131 to 140 of about 153,260 (300)

The Burden of Antimicrobial‐Resistant Pseudomonas aeruginosa Isolates in Children With Cystic Fibrosis: Molecular Characterization and Genotyping Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study highlights the prevalence of multidrug‐ and carbapenem‐resistant Pseudomonas aeruginosa in pediatric cystic fibrosis patients, along with the presence of carbapenemase‐encoding genes and genetic profiles, suggesting clonal spread. These findings underscore the urgent need for surveillance and strategies to combat resistant strains and ...
Erfaneh Jafari, Babak Pourakbari, Mohammad Reza Asadi Karam, Reza Azizian, Mohammad Reza Modaresi, Setareh Mamishi   +5 more
wiley   +1 more source

Prediction of Antibiotic Influence by Presence of Some β-lactamase Gene in AcinetobacterInfected Patients Hospitalized in Tehran, Iran [PDF]

Acinetobacter baumannii which is gram-negative rod and infecting hospitalized patient often develops multiple drug resistance patterns and causes serious problem in treatment.
آقابزرگی, سهراب, امانی, فیروز, اکبری, مهدی, دادگر پاکدل, جواد, دادگر پاکدل, فاطمه, رسولی, ایرج, نیاکان, محمد, کاظمی, سهیلا, یادگاری نیا, داوود   +8 more
core  

Septic Shock Caused by Coinfection of Shewanella algae Bloodstream Infection and Epstein‐Barr Virus: Clinical Characteristics and Genomic Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study reports a septic shock case in inland China caused by coinfection of Shewanella algae bloodstream infection and Epstein‐Barr virus. Genomic analysis revealed freshwater adaptation of the strain via unique genes for transporters and carbohydrate‐active enzymes.
Jianmei Chen, Dong Ling, Feng Wang, Liping Liu, Yucheng Ren, Chengying Chen, Na Su   +6 more
wiley   +1 more source

Bench‐Stable Boryl Thianthrenium Dication Enables Aziridinyl Boronate Synthesis via Metal‐Free Late‐Stage Aziridination with Diverse Nitrogen Nucleophiles

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
A bench‐stable boryl thianthrenium dication is synthesized via thianthrenation of vinyl MIDA boronate. This novel dication enables metal‐free, chemo‐, and diastereoselective late‐stage aziridination with diverse nitrogen nucleophiles. The strategic significance is further showcased by one‐pot electrochemical and asymmetric protocols and versatile ...
Veerabhadra R. Vulupala, Disni Gunasekera, Nagarjun R. Mallampudi, Ramy Yousef, Yusif I. Gyasi, Gopal R. Ramidi, Ifeoluwa Adedotun, Shiqing Xu   +7 more
wiley   +2 more sources

Antibiotic Resistance, Biofilm Genes, and smeDEF Efflux Pump in Clinical Stenotrophomonas maltophilia Isolates From Iran

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Iranian clinical Stenotrophomonas maltophilia isolates showed high susceptibility to trimethoprim/sulfamethoxazole, minocycline, and levofloxacin, but marked resistance to ceftazidime and ticarcillin‐clavulanate, alongside widespread biofilm production and resistance genes.
Haneen Fadhil Jasim, Nisreen Salah Majeed, Asmaa A. Salam, Rania Hameed Hamad, Yeganeh Behrouzi, Erta Rajabi, Razieh Shahbazi   +6 more
wiley   +1 more source

Pharmacokinetics and Customized Dosing of Vancomycin in Adult Patients With Hematological Malignancies: Status, Challenges, and Opportunities

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
Framework diagram of CDvan informed by MCS (Eucast, European committee for antimicrobial susceptibility testing; CLSI, clinical and laboratory standard institute). ABSTRACT Vancomycin (VAN) remains the first‐line treatment for methicillin‐resistant, multidrug‐resistant gram‐positive bacterial infections, even among cancer patients.
Xiangqing Song, Meizi Zeng, Tao Yang, Mi Han   +3 more
wiley   +1 more source

Recent Advances in Metal‐Organic Framework‐Integrated Nanocomposite Hydrogels for Sensors and Sensing Systems

SmartMat, Volume 7, Issue 1, February 2026.
Metal‐organic framework–hydrogel composites are explored as multifunctional materials for next‐generation sensors and sensing systems. This review summarizes recent advances in employing these smart composites to fabricate optical, electrochemical, and electromechanical sensors, emphasizing their potential in healthcare, biomedical diagnostics ...
Md Sazzadur Rahman, Emna Helal, Nicole R. Demarquette   +2 more
wiley   +1 more source

Discovery of Quercetin and Its Analogs as Potent OXA-48 Beta-Lactamase Inhibitors. [PDF]

Front Pharmacol, 2022
Zhang Y, Chen C, Cheng B, Gao L, Qin C, Zhang L, Zhang X, Wang J, Wan Y.   +8 more
europepmc   +1 more source

Sepsis secondary to cystitis in a guinea pig (Cavia porcellus)

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract Cystitis is a frequent, often chronic and recurrent disease in guinea pigs (Cavia porcellus). This report describes a case of a 2‐year‐old, entire, female Abyssinian guinea pig with fatal cystitis. The animal was presented with progressive chronic cystitis and had previously been treated with several antibiotics and analgesics.
Anika Mische, Katharina Landmann, Lars Mundhenk, Antina Lübke‐Becker, Kerstin Müller   +4 more
wiley   +1 more source

Dicloxacillin and Flucloxacillin Inhibit Hepatic Uptake Transporters—In Vitro Investigations and Physiologically Based Pharmacokinetic Modeling

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Dicloxacillin and flucloxacillin are β‐lactamase‐resistant penicillin antibiotics that have been in clinical use for over 50 years. While both antibiotics are known to induce cytochrome P450 enzymes, there is limited information available regarding their interactions with drug transporters.
Noora Sjöstedt, Ogochukwu U. Amaeze, Jeroen J. M. W. van den Heuvel, Tore B. Stage, Jan B. Koenderink, Nina Isoherranen, Heidi Kidron, Erkka Järvinen   +7 more
wiley   +1 more source