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Insight into the screening of potential beta-lactamase inhibitors as anti-bacterial chemical agents through pharmacoinformatics study

Journal of Biomolecular Structure and Dynamics, 2021
Pratap Parida   +2 more
exaly  

Evolution of beta-lactamase inhibitors.

Pharmacotherapy, 1991
After the introduction of penicillin G into therapeutics, bacteria became increasingly resistant to this penicillin and subsequent beta-lactam antibiotics. The major cause of this resistance is beta-lactamase, an enzyme produced by the bacterium, that destroys the antibiotic before it reaches its target within the bacterial cell.
openaire   +1 more source

Carbapenems versus beta-lactam/beta-lactamase inhibitors to treat ESBL-producing Enterobacteriaceae infections

Médecine Et Maladies Infectieuses, 2020
J P Bru   +2 more
exaly  

Implications of beta-lactamase-inhibitor combinations.

The Journal of reproductive medicine, 1988
Ticarcillin disodium/clavulanate potassium and other beta-lactamase inhibitor/penicillin combinations have been recognized recently as broad-spectrum drugs that have a major role in chemotherapy for serious surgical sepsis. Their spectrum of activity allows the economical substitution of ticarcillin disodium/clavulanate potassium for anaerobe-active ...
openaire   +1 more source

[Beta-lactamase inhibitors].

Nihon rinsho. Japanese journal of clinical medicine, 1992
H, Nishiya, O, Kunii
openaire   +1 more source

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