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Antibiotic Resistance in <i>Klebsiella pneumoniae</i> and Related Enterobacterales: Molecular Mechanisms, Mobile Elements, and Therapeutic Challenges. [PDF]
Zdarska V +3 more
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Medical dispensation in La Rioja, Spain: epidemiology and its relationship with social determinants: a descriptive study. [PDF]
Aparicio-Rodríguez G +9 more
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beta-lactamase epidemiology and the utility of established and novel beta-lactamase inhibitors
Expert Opinion on Investigational Drugs, 2000beta-Lactamase inhibitor:beta-lactam combinations remain one of the most successful strategies for the treatment of bacterial infections. Over the last 20 years the number and diversity of serine and metallo active site beta-lactamases has increased dramatically. This review highlights some of the new additions to the beta-lactamase arena and discusses
D J, Payne, W, Du, J H, Bateson
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A 2018–2019 patent review of metallo beta-lactamase inhibitors
Expert Opinion on Therapeutic Patents, 2020Introduction Antibiotic resistance caused by beta-lactamase expressing bacteria poses a concern given its global dissemination and proliferation. The emergence of the metallo beta-lactamases is an indefinite health threat toward which current antibiotics
Nakita Reddy +6 more
semanticscholar +1 more source
Journal of Biomolecular Structure and Dynamics, 2020
Drug resistance is an unsolved and major concern in the bacterial infection. Continuous development of drug-resistance to the antibiotics exponentially rises the danger of bacterial infections.
P. Parida +3 more
semanticscholar +1 more source
Drug resistance is an unsolved and major concern in the bacterial infection. Continuous development of drug-resistance to the antibiotics exponentially rises the danger of bacterial infections.
P. Parida +3 more
semanticscholar +1 more source
Beta-lactamase inhibitor combinations
Medical Clinics of North America, 1995The beta-lactamase inhibitor combinations present a novel approach to the problem of beta-lactamase-induced resistance to antibiotics. These agents are derived from the generally safe beta-lactam class of antibiotics. They are all principally excreted through the kidneys and require dosage adjustment in the face of significant renal insufficiency. They
J W, Sensakovic, L G, Smith
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