Results 101 to 110 of about 60,277 (349)

Iridium‐Catalyzed Linear‐Selective sp3 C−H Alkylation of N‐Methylamides Using Alkenes Enabled by Diphosphite Ligands

open access: yesChemistry – A European Journal, EarlyView.
An iridium‐catalyzed linear‐selective sp3 C─H alkylation of N‐methylamides with alkenes is described. This method tolerates various N‐methylacetamide derivatives and has a broad alkene scope. Mechanistic studies were also conducted. Internal alkenes can also be used through in situ consecutive alkene isomerization.
Haluhi Takahashi, Takanori Shibata
wiley   +1 more source

Effective screening of antibiotic and coccidiostat residues in food of animal origin by reliable broad-spectrum residue screening tests

open access: yesItalian Journal of Animal Science, 2020
Foods of animal origin are controlled for antibiotic and coccidiostat residues. The rapid residue detection is possible using reliable broad-spectrum screening tests.
Ivona Kožárová   +4 more
doaj   +1 more source

Population pharmacokinetics at two dose levels and pharmacodynamic profiling of flucloxacillin [PDF]

open access: yes, 2007
Flucloxacillin is often used for the treatment of serious infections due to sensitive staphylococci. The pharmacokinetic (PK)-pharmacodynamic (PD) breakpoint of flucloxacillin has not been determined by the use of population PK.
Bulitta, J. B.   +6 more
core   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

open access: yesChemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis   +2 more
wiley   +1 more source

Parenteral antibiotics at home [PDF]

open access: yes, 2012
Giving parenteral antibiotics to patients at home compared to in hospital presents unique ...
Looke, David F. M.   +1 more
core   +1 more source

The Visual Predictive Check and Real‐World Data

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The visual predictive check (VPC) is a standard tool for assessing pharmacometric model suitability, producing visualizations that compare observed data with simulated data such that both model structure and model variability terms can be assessed. However, real‐world data commonly reflect clinical decision‐making that adapts therapy in response to ...
Jasmine H. Hughes   +2 more
wiley   +1 more source

Antibacterial Activity of Heteropolytungstates Against Proteus mirabilis

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
We investigated the in vitro antibacterial activity of several heteropolytungstates against P. mirabilis, a drug‐resistant pathogen. All tested polyanions inhibited bacterial growth, with the Preyssler–Pope–Jeannin polyanion P5W30 exhibiting the highest activity (MIC = 0.78 mg/mL).
Nour El Ghouch   +5 more
wiley   +1 more source

Perioperative infection prophylaxis and risk factor impact in colon surgery [PDF]

open access: yes, 2000
Background: A prospective observational study was undertaken in 2,481 patients undergoing elective colon resection in 114 German centers to identify optimal drug and dosing modalities and risk factors for postoperative infection.
Kohler, L.   +5 more
core   +1 more source

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