Results 81 to 90 of about 612,998 (297)

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

open access: yesNature Communications, 2016
Bacterial beta-lactamases are responsible for resistance to beta-lactams, the most important family of antibiotics. Here, the authors reveal cyclic boronate inhibitors that are active against both serine- and metallo-beta-lactamases and represent a ...
Jürgen Brem   +9 more
doaj   +1 more source

Acinetobacter nosocomialis: Defining the Role of Efflux Pumps in Resistance to Antimicrobial Therapy, Surface Motility, and Biofilm Formation

open access: yesFrontiers in Microbiology, 2018
Acinetobacter nosocomialis is a member of the Acinetobacter calcoaceticus-Acinetobacter baumannii (ACB) complex. Increasingly, reports are emerging of the pathogenic profile and multidrug resistance (MDR) phenotype of this species.
Daniel B. Knight   +9 more
doaj   +1 more source

Phi Beta Kappa: The Key Reporter Winter 2012-2013 [PDF]

open access: yes, 2012
Announcement of the Beta of Nebraska chapter installation at Creighton University, p.
Phi Beta Kappa Society
core  

Fluoroquinolone Versus Nonfluoroquinolone Treatment of Bloodstream Infections Caused by Chromosomally Mediated AmpC-Producing Enterobacteriaceae

open access: yesAntibiotics, 2020
Objectives: Chromosomally mediated AmpC-producing Enterobacteriaceae (CAE) display high susceptibility to fluoroquinolones; minimal clinical data exist supporting comparative clinical outcomes.
Sarah Grace Gunter   +3 more
doaj   +1 more source

Bifunctional Asymmetric Catalysis:  A Tandem Nucleophile/Lewis Acid Promoted Synthesis of β-Lactams [PDF]

open access: yes, 2016
We describe a superior procedure for the catalytic, asymmetric synthesis of β-lactams using a bifunctional catalyst system consisting of a chiral nucleophile and an achiral Lewis ...
Ahmed M. Hafez (2714233)   +5 more
core   +1 more source

SYNTHESIS OF HETEROCYCLES THROUGH BETA LACTAMS RING RUPTURE [PDF]

open access: yes, 2018
Many Beta lactams are widely used as medicines. The 4-membered ring present in the beta lactams is under strain and therefore, it can undergo cleavage reactions to diverse compounds.
Banik, Bimal K.
core   +1 more source

Acid-dependent beta-lactam resistance in Klebsiella pneumoniae is mediated by paralogous class B PBPs and the class A PBP, PBP1b

open access: yesmBio
Klebsiella pneumoniae is a leading cause of global deaths due to antibiotic resistance. Of particular concern is the rapid expansion of resistance to beta-lactam antibiotics within K. pneumoniae lineages. The environmental factors that influence pathogen
Sarah Beagle, Petra Anne Levin
doaj   +1 more source

Beta lactam antibiotics residues in cow's milk: comparison of efficacy of three screening tests used in Bosnia and Herzegovina

open access: yesBiomolecules & Biomedicine, 2014
Beta lactam antibiotics are widely used in therapy of cattle, particularly for the treatment of mastitis.  Over 95% of residue testing in dairies in Bosnia and Herzegovina is for Beta lactams.
Nihad Fejzic   +3 more
doaj   +1 more source

Beta-lactam antibiotic test doses in the emergency department

open access: yesWorld Allergy Organization Journal, 2020
Background: Facilitating beta-lactam antibiotic use in patients reporting beta-lactam allergies in acute care settings is important to individual patient outcomes and public health; however, few initiatives have targeted the Emergency Department (ED ...
Michelle Maguire   +9 more
doaj   +1 more source

A facile synthesis of new beta-lactams [PDF]

open access: yes, 1996
Several new beta-lactams have been synthesized in good yields, via the cyclization of 3-chloro-N-arylpropionamides in a mixture of N,N-dimethylformamide and anhydrous sodium carbonate under a nitrogen ...
H. ElKashef   +6 more
core  

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