Results 171 to 180 of about 612,998 (297)

Likelihood of aggressive PK/PD target attainment of continuous-infusion beta-lactams during the first week of treatment of febrile neutropenia: findings from a 1-year prospective, monocentric study in onco-haematological patients. [PDF]

J Antimicrob Chemother
Cojutti PG, Toschi A, Pasquini Z, Paolini S, Maffini E, Bonifazi F, Zinzani PL, Giannella M, Viale P, Pea F.   +9 more
europepmc   +1 more source

Clinical Outcomes With Extended Versus Intermittent Infusion of Anti-Pseudomonal Beta-Lactams in Patients With Gram-Negative Bacteremia. [PDF]

Open Forum Infect Dis, 2023
Tran NN, Mynatt RP, Kaye KS, Zhao JJ, Pogue JM.   +4 more
europepmc   +1 more source

Quality and Consistency of Penicillin Allergy Delabelling Guidelines: A Systematic Review

Clinical &Experimental Allergy, EarlyView.
Eighteen penicillin allergy delabelling guidelines from 12 countries were reviewed. There is consensus for staged risk‐based testing, with emerging support for direct oral challenge in low‐risk patients and expanded non‐specialist roles. Overall guideline quality was low, with major gaps in methodological rigour, stakeholder involvement, and ...
Jessie He, Marina Guirguis, Sankare Devanandan, Rani Scott‐Farmer, Sandra Vale, Michaela Lucas, Jennifer J. Koplin, Catherine J. Hornung, Sandra M. Salter   +8 more
wiley   +1 more source

Assessment of Patients With Beta-Lactams Positive Provocation Tests by Biomarkers of IgG-Related Neutrophil Activation. [PDF]

Clin Exp Allergy
Gallizzi AA, Guéant-Rodriguez RM, Boteanu C, Alberto JM, Lakomy C, Louis H, Chery C, Renard P, Regnault V, Safar R, Heinken A, Romano A, Laguna JJ, Guéant JL.   +13 more
europepmc   +1 more source

Azithromycin Versus Beta-lactams in Hospitalized Patients with Acute Exacerbations of COPD. [PDF]

J Gen Intern Med, 2022
Baalbaki N, Giuliano C, Hartner CL, Kale-Pradhan P, Johnson L.   +4 more
europepmc   +1 more source

A Hunt for the Resistance of Haemophilus influnezae to Beta-Lactams. [PDF]

Antibiotics (Basel)
Denizon M, Hong E, Terrade A, Taha MK, Deghmane AE.   +4 more
europepmc   +1 more source

A Review of Extended and Continuous Infusion Beta-Lactams in Pediatric Patients. [PDF]

J Pediatr Pharmacol Ther, 2022
Imburgia TA, Kussin ML.
europepmc   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, EarlyView.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source

Therapeutic Drug Monitoring of Beta-Lactams in Cystic Fibrosis: Unattained Target in Standard Antibiotic Dosing. [PDF]

Ther Drug Monit
Maraczek Markova E, Stastna N, Fila L, Horska K.   +3 more
europepmc   +1 more source

Cryo‐EM structures of multiple‐peptide resistance factor (MprF) from Pseudomonas aeruginosa

The FEBS Journal, EarlyView.
Cryo‐EM analysis of MprF from Pseudomonas aeruginosa reveals a dimeric enzyme, distinct from Rhizobium homologues. The soluble GNAT domain contains a dynamic amphipathic helix (TTH) that adopts different positions in detergent micelle and nanodisc, relative to the membrane.
Shaileshanand Jha, Kutti R. Vinothkumar
wiley   +1 more source