Results 281 to 290 of about 60,277 (349)
A Bifunctional Protease Cleaves the Leader Peptide in the Biosynthesis of Class I Microviridins
ChemBioChem, Volume 27, Issue 7, 14 April 2026.Biochemical characterization of the peptidase candidate NosP reveals bifunctional endo‐ and aminopeptidase activity in the leader peptide removal of class I microviridins from Nostoc punctiforme. The discovery of the first leader‐processing peptidase from microviridin biosynthesis may pave the way for the efficient production and bioengineering of ...
Nico Brüssow +7 more
wiley +1 more source
Metalloids: Semi as Metals yet Full of Antimicrobial Potential
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm +2 more
wiley +1 more source
The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia +4 more
wiley +1 more source