Results 291 to 300 of about 60,277 (349)
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Monocyclic antibiotic .beta.-lactams
Journal of Medicinal Chemistry, 1975The preparation and antimicrobial activity of a series of beta-lactams (3a-f) are described. These compounds were prepared from the 2+2 cycloaddition of beta,beta-disubstituted enamines with aryl isocyanates; compounds 3a-f underwent facile beta-lactam ring fission between aminal carbon atom C4 and the lactam nitrogen N1.
R F, Abdulla, K H, Fuhr
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Beta‐lactam biosynthetic genes
Medicinal Research Reviews, 1989Article de synthese sur les genes impliques dans la biosynthese des beta-lactam; clonage moleculaire et expression chez E.
T D, Ingolia, S W, Queener
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Enfermedades infecciosas y microbiologia clinica, 2003
Betalactams, which act by inhibiting the last phase of bacterial cell wall synthesis, constitute the largest family of antimicrobial agents and the most extensively used in current clinical practice. These drug have a slow bactericidal action that is relatively independent of plasma concentrations, little toxicity and a broad therapeutic margin.
Mar, Marín, Francesc, Gudiol
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Betalactams, which act by inhibiting the last phase of bacterial cell wall synthesis, constitute the largest family of antimicrobial agents and the most extensively used in current clinical practice. These drug have a slow bactericidal action that is relatively independent of plasma concentrations, little toxicity and a broad therapeutic margin.
Mar, Marín, Francesc, Gudiol
openaire +1 more source