Results 161 to 170 of about 7,983 (189)

[Beta-mannosidase of trophoblast and humana skin fibroblasts].

Biulleten' eksperimental'noi biologii i meditsiny, 1992
Conditions for assay of beta-mannosidase activity in human chorionic villi were studied using the fluorogenic substrate 4-methylumbelliferyl-beta-D-mannopyranoside. Comparison of the biochemical properties of the chorionic villi beta-mannosidase with those of the enzyme from human cultured fibroblasts showed their similarity.
N A, Petushkov, T S, Ivleva
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Morphological and biochemical studies of human beta-mannosidosis: identification of a novel beta-mannosidase gene mutation

British Journal of Dermatology, 2003
There are seven well-known lysosomal storage diseases that produce angiokeratoma corporis diffusum clinically. beta-Mannosidosis (MANB1; OMIM248510), first reported in humans in 1986, is a rare hereditary lysosomal storage disease caused by a deficiency of the enzyme beta-mannosidase.
Y, Uchino, T, Fukushige, S, Yotsumoto, T, Hashiguchi, H, Taguchi, N, Suzuki, I, Konohana, T, Kanzaki   +7 more
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A Novel alpha1,2-L-fucosidase acting on xyloglucan oligosaccharides is associated with endo-beta-mannosidase.

Journal of biochemistry, 2008
Endo-beta-mannosidase, which hydrolyses the Manbeta1-4GlcNAc linkage of N-glycans in an endo-manner, was discovered in plants. During the course of the purification of the enzyme from lily flowers, we found a higher molecular mass form of the enzyme (designated as EBM II).
Takeshi, Ishimizu, Chikako, Hashimoto, Ryo, Takeda, Kenta, Fujii, Sumihiro, Hase   +4 more
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β-Mannosidase from Thermotoga species

2001
Publisher Summary β -Mannosidase is an exo-acting glycosylhydrolase whose function is to cleave mannose residues from the nonreducing termini of mannan oligosaccharides. In microorganisms, β -mannosidases often act in concert with endo-acting β -mannanases to completely hydrolyze mannan-based carbohydrates to be subsequently used for nutritional ...
K N, Parker, S, Chhabra, D, Lam, M A, Snead, E J, Mathur, R M, Kelly   +5 more
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The properties of synovial fluid β-mannosidase activity

Biochimica et Biophysica Acta (BBA) - Enzymology, 1973
Abstract The aim of the present study was to evaluate the β-mannosidase activity (β- d -mannoside mannohydrolase, EC 3.2.1.25) of human synovial fluid. It was shown to have a pH requirement of 3.5–4.0 and a K m value of 3.4·10−3 M using a p- nitro-phenyl-β-mannopyranoside as the substrate.
B A, Bartholomew, A L, Perry
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Purification and characterization of beta-mannosidase from human placenta.

Journal of biochemistry, 1989
Lysosomal beta-mannosidase was purified almost 10,000-fold from human placenta. The final preparation showed several protein bands on polyacrylamide gel electrophoresis. Its molecular mass was estimated to be 110 kDa, the optimal pH was 4.5, the Km was 0.56 mM, and the isoelectric point was 4.7.
Y, Iwasaki, A, Tsuji, K, Omura, Y, Suzuki   +3 more
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β-mannosidase in human serum and urine. A comparative study

International Journal of Biochemistry, 1986
All serum and urine beta-mannosidase activities are adsorbed on a DEAE-Trisacryl column at pH 6. Only one form is eluted with a NaCl linear gradient. The two enzymes, isolated from either serum or urine exhibit similar properties. Slight differences are only observed in thermostability and molecular weight.
M, Bernard, M, Sioud, F, Percheron, M J, Foglietti   +3 more
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Plasma alpha- and beta-mannosidase activities in caprine beta-mannosidosis.

American journal of veterinary research, 1982
Plasma alpha- and beta-mannosidase activities were measured in goats with beta-mannosidosis, a recently discovered, inherited deficiency of the glycohydrolase beta-D-mannosidase. Plasma beta-mannosidase activity in the affected animals was zero at 1 and 4 weeks after they were born. Enzyme values of age-matched, unaffected goats were between 66 and 222
K, Cavanagh, R W, Dunstan, M Z, Jones
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Human β‐mannosidase deficiency associated with peripheral neuropathy

Annals of Neurology, 1994
AbstractHuman β‐mannosidosis is an inherited lysosomal storage disorder described in only seven families. We present a further case in a black African 14‐year‐old boy with severely deficient β‐mannosidase activity, bilateral thenar and hypothenar amyotrophy, electrophysiologically demonstrable demyelinating peripheral neuropathy, and cytoplasmic ...
T, Levade, D, Graber, V, Flurin, M B, Delisle, M T, Pieraggi, M F, Testut, J P, Carrière, R, Salvayre   +7 more
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Activity of alpha- and beta-mannosidases in semen and reproductive organs of the drake.

Reproductive biology, 2009
The activity of alpha- and beta-mannosidase (alpha-MAN and beta-MAN) in seminal plasma, spermatozoa and homogenates of reproductive organs has been determined in the drake. The highest specific activities of the examined mannosidases were found in epididymides.
Małgorzata, Dzugan, Juliusz, Ksiazkiewicz   +1 more
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