Results 91 to 100 of about 1,338,554 (258)
Beta 2-adrenoceptor stimulation increases the number of antigen-specific precursor B lymphocytes that differentiate into IgM-secreting cells without affecting burst size [PDF]
V M Sanders, Frances E. Powell-Oliver
openalex +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Lepton Number Violation: from $0\nu\beta\beta$ Decay to Long-Lived Particle Searches [PDF]
Gang Li +3 more
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Revealing Fibroblast Growth Factor Receptor-1 and Klotho-Beta Plasma Membrane Dynamics with FRAP and Number and Brightness Analysis [PDF]
Aaron Y.K. Ming +4 more
openalex +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
The smallest singular value anomaly: The reasons behind sharp anomaly
Let AA be an arbitrary matrix in which the number of rows, mm, is considerably larger than the number of columns, nn. Let the submatrix Ai,i=1,…,m{A}_{i},\hspace{0.33em}i=1,\ldots ,m, be composed from the first ii rows of AA, and let βi{\beta }_{i ...
Dax Achiya
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The Effect Of Kersen (<i>Muntingia calabura</i>) Extract On The Number Of Pancreatic Beta Cells: Experiment Study In Rat [PDF]
Sri Mega Muthmainah S.P +3 more
openalex +1 more source

