Results 91 to 100 of about 1,317,896 (291)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

THE EFFECT OF BETA GLUCAN OF SACCHAROMYCES CEREVISAE ON THE INCREASE OF THE NUMBER OF BRAIN CELLS IN SUBSTANTIA NIGRA BRAIN OF PARKINSON’S WISTAR STRAIN RAT (RATTUS NORVEGICUS) MODEL INDUCED WITH ROTENONE

open access: yesMalang Neurology Journal, 2015
ackground and aims. One of many neurodegenerative diseases afflicting the elderly is Parkinson. Beta glucan from Saccharomyces cerevisae is very potential to be used as a regenerative therapy of Parkinson's disease.
Masruroh Rahayu   +2 more
doaj   +1 more source

TeV-scale Lepton Number Violation: Connecting Leptogenesis, Neutrinoless Double Beta Decay, and Colliders [PDF]

open access: green, 2021
Julia Harz   +3 more
openalex   +1 more source

User manual for Meta-Essentials: Workbooks for meta-analyses (Version 1.3) [PDF]

open access: yes, 2018
Meta-Essentials is a set of workbooks that facilitate the integration and synthesis of effect sizes from different studies and provide figures, tables, and statistics that might be helpful for interpreting them.
Hak, A. (Tony)   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Corporate Financial Policies and Performance Around Currency Crises [PDF]

open access: yes
Using data from 17 countries that have suffered a currency crisis, this paper studies firm-level leverage and performance measures before and after a crisis has occurred.
Bris, Arturo   +2 more
core  

Great Expectatrics: Great Papers, Great Journals, Great Econometrics [PDF]

open access: yes
The paper discusses alternative Research Assessment Measures (RAM), with an emphasis on the Thomson Reuters ISI Web of Science database (hereafter ISI). The various ISI RAM that are calculated annually or updated daily are defined and analysed, including
Chia-Lin Chang   +2 more
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

331 Validation of a Novel CSF-Based Biomarker of Mitochondrial Function

open access: yesJournal of Clinical and Translational Science
OBJECTIVES/GOALS: Determine the exosome mitochondrial DNA (mtDNA) copy number in cerebrospinal fluid (CSF) as a measure of neuronal mitochondrial integrity in patients with subarachnoid hemorrhage (SAH).
Dhanushki Abeykoon   +5 more
doaj   +1 more source

Health Inequality, Education and Medical Innovation [PDF]

open access: yes
Recent studies suggest that health inequalities across socio-economic groups in the US are large and have been growing. We hypothesize that, as in other, non-health contexts, this pattern occurs because more educated people are better able than to take ...
Adriana Lleras-Muney, Sherry Glied
core  

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