Results 101 to 110 of about 11,073,196 (295)
Existence of solutions for semilinear problems with prescribed number of zeros on exterior domains
In this article we prove the existence of an infinite number of radial solutions of $\Delta(u)+f(u)=0$ with prescribed number of zeros on the exterior of the ball of radius R>0 centered at the origin in $\mathbb {R}^N$ where f is odd with f0 on ...
Janak Joshi, Joseph Iaia
doaj
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad+13 more
wiley +1 more source
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran+16 more
wiley +1 more source
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa+13 more
wiley +1 more source
Antibacterial effect of beta-thujaplicin on staphylococci isolated from atopic dermatitis: relationship between changes in the number of viable bacterial cells and clinical improvement in an eczematous lesion of atopic dermatitis [PDF]
Youichi Arima
openalex +1 more source
Synthesis of new α,β-unsaturated butenolides
A number of new &gama;-substituted α,β-unsaturated butenolides have been synthesized by the condensation of phenols with β-(3-nitrobenzoyl)acrylic acid and β-(4-methyl-3-nitrobenzoyl)acrylic acid.
Veena Joshi, R.P. Chamoli
doaj
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen+6 more
wiley +1 more source
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti+8 more
wiley +1 more source
On gaps in Rényi \beta -expansions of unity for \beta > 1 an algebraic number [PDF]
Jean-Louis Verger-Gaugry
openalex +1 more source