Results 201 to 210 of about 88,568 (304)

Salvianolic acid A facilitates cartilage repair in knee osteoarthritis model rats by promoting WDR5 expression. [PDF]

Regen Ther
He H, Dong D.
europepmc   +1 more source

The Sunrise of Tertiary Lymphoid Structures in Cancer

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT First considered as a negative epiphenomenon in autoimmune and inflammatory diseases, with possible deleterious consequences through the production of pathological autoantibodies and antiself T cells, tertiary lymphoid structures (TLS) have gained major scientific and clinical interest in cancer due to their association with better clinical ...
Juliette Rochefort, Gilles Marodon, Jean‐Luc Teillaud, Marie‐Caroline Dieu‐Nosjean   +3 more
wiley   +1 more source

Mechanism of Fatty Acid Metabolism and Regulation by Lactate During Exercise in White Adipose and Skeletal Muscle Tissue: A Review. [PDF]

Sports Med Open
Huang S, Shangguan R, Chen S, Lai X, Han H, Sun J.   +5 more
europepmc   +1 more source

Impact of Drug–Drug Interactions on Clinical Outcomes in Metastatic Melanoma Patients Treated With Combined BRAF/MEK Inhibitors: A Real‐World Study

Pigment Cell &Melanoma Research, Volume 38, Issue 4, July 2025.
ABSTRACT The unique pharmacokinetics of BRAF and MEK inhibitors make patients vulnerable to drug–drug interactions (DDIs), which may compromise treatment efficacy in metastatic melanoma. This study evaluates the impact of DDIs on clinical outcomes in patients with metastatic melanoma treated with BRAF/MEK inhibitors.
Silvia Mezi, Andrea Botticelli, Giulia Pomati, Simone Scagnoli, Giulia Fiscon, Federica de Galitiis, Francesca Romana di Pietro, Sofia Verkhovskaia, Sasan Amirhassankhani, Giovanna Gentile, Maurizio Simmaco, Bjoern Gohlke, Robert Preissner, Daniele Santini, Paolo Marchetti   +14 more
wiley   +1 more source

PGC-1α Activation by Polyphenols: A Pathway to Thermogenesis. [PDF]

Mol Nutr Food Res
Vannuchi N, Pisani L.
europepmc   +1 more source

Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease

Experimental Physiology, Volume 110, Issue 7, Page 918-935, 1 July 2025.
Abstract Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine signalling and inter‐organ communication. Traditionally seen as passive entities, metabolites
Anna Malicka, Aysha Ali, Amanda D. V. MacCannell, Lee D. Roberts   +3 more
wiley   +1 more source

β₂-Adrenergic Receptor Agonists in Diabetic Kidney Disease: Exploring a New Frontier. [PDF]

Biochem Res Int
Hegde S, Chogtu B, Magazine R, Magazine R, Prabhu R.   +4 more
europepmc   +1 more source

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

European Journal of Organic Chemistry, Volume 28, Issue 23, June 23, 2025.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source

The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance [PDF]

, 2009
Ersilia Cipolletta, Alfonso Campanile, Gaetano Santulli, Emma Sanzari, Dario Leosco, Pietro Campiglia, Bruno Trimarco, Guido Iaccarino   +7 more
openalex   +1 more source

Beta-blockers prolong response to androgen deprivation therapy in prostate cancer through modulation of the neuro-immuno-oncology axis. [PDF]

J Transl Med
Thulin MH, Ramberg H, Nielsen HK, Grytli HH, Sivanesan S, Pandya AD, Seip K, Andressen KW, Linder A, Øijordsbakken M, Poutanen M, Katz B, Halvorsen B, Mælandsmo GM, Taskén KA.   +14 more
europepmc   +1 more source