Results 121 to 130 of about 8,513,926 (380)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Aerodynamic Design Optimization of a Micro Radial Compressor of a Turbocharger

open access: yesEnergies, 2018
This study presents an aerodynamic design optimization of a micro radial compressor impeller on a turbocharger used in a 0.8 L two-cylinder gasoline engine.
Omer Faruk Atac   +2 more
doaj   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Application of the Beta Distribution for the Temporal Quantification of Storm Events

open access: yes, 2012
This study suggested the parameter estimation method for given rainfall events to be properly expressed by the beta distribution. For this purpose, this study compared the characteristics of probability density function with the parameter proposed ...
C. Jun, C. Yoo
semanticscholar   +1 more source

Approximation of Rectangular Beta-Laguerre Ensembles and Large Deviations [PDF]

open access: yes, 2013
We investigate the random eigenvalues coming from the beta-Laguerre ensemble with parameter p, which is a generalization of the real, complex and quaternion Wishart matrices of parameter (n,p).
Danning Li   +4 more
core   +3 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Some Relationships and Properties of the Hypergeometric Distribution [PDF]

open access: yesarXiv, 2016
The binomial and Poisson distributions have interesting relationships with the beta and gamma distributions, respectively, which involve their cumulative distribution functions and the use of conjugate priors in Bayesian statistics. We briefly discuss these relationships and some properties resulting from them which play an important role in the ...
arxiv  

The beta log-logistic distribution [PDF]

open access: yesBrazilian Journal of Probability and Statistics, 2014
A new continuous distribution, so-called the beta log-logistic distribution, that extends the log-logistic distribution and some other distributions is proposed and studied. The new model is quite flexible to analyze positive data. Various structural properties of the new distribution are derived, including explicit expressions for the moments, mean ...
openaire   +2 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Generating Realistic Labelled, Weighted Random Graphs

open access: yesAlgorithms, 2015
Generative algorithms for random graphs have yielded insights into the structure and evolution of real-world networks. Most networks exhibit a well-known set of properties, such as heavy-tailed degree distributions, clustering and community formation ...
Michael Charles Davis   +5 more
doaj   +1 more source

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