Results 41 to 50 of about 6,189,777 (260)
MathematicsSuppose that bids, or offers, to purchase an asset for sale occur according to a non-homogeneous Poisson process. Bid amounts, measured in percentages, are assumed to be independent and identically distributed random variables. Faced with the pressure of
Steve Drekic
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Confluent Hypergeometric Beta Distribution
Mathematics, 2023 The confluent hypergeometric beta distribution due to Gordy has been known since the 1990s, but not much of is known in terms of its mathematical properties.
Saralees Nadarajah, Malick Kebe
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Bernstein-type bounds for beta distribution
Modern Stochastics: Theory and Applications, 2023 This work obtains sharp closed-form exponential concentration inequalities of Bernstein type for the ubiquitous beta distribution, improving upon sub-Gaussian and sub-gamma bounds previously studied in this context.
Maciej Skorski
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The Beta Maxwell Distribution [PDF]
, 2010 In this work we considered a general class of distributions gener- ated from the logit of the beta random variable. We looked at various works that have been done and discussed some of the results that were obtained.
Amusan, Grace Ebunoluwa
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
On the Beta-Nakagami Distribution [PDF]
, 2013 This study is focused on combining Nakagami distribution and beta distribution with a view to obtaining a distribution that is better than each of them individually in terms of the estimate of their characteristics and parsimonious in their parameters ...
Shittu, Olanrewaju I. +1 more
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Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source