Results 51 to 60 of about 1,748,610 (284)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Hierarchical Dynamic Beta Model
We develop a hierarchical dynamic Bayesian beta model for modelling a set of time series of rates or proportions. The proposed methodology enables to combine the information contained in different time series so that we can describe a common underlying ...
Cibele Queiroz Da-Silva +1 more
doaj +1 more source
Applications of Ideas from Random Matrix Theory to Step Distributions on "Misoriented" Surfaces
Arising as a fluctuation phenomenon, the equilibrium distribution of meandering steps with mean separation $$ on a "tilted" surface can be fruitfully analyzed using results from RMT. The set of step configurations in 2D can be mapped onto the world lines
Einstein, T. L.
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The Confluent Hypergeometric Beta Distribution
The confluent hypergeometric beta distribution due to Gordy has been known since the 1990s, but not much of is known in terms of its mathematical properties.
Saralees Nadarajah, Malick Kebe
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Bernstein-type bounds for beta distribution
This work obtains sharp closed-form exponential concentration inequalities of Bernstein type for the ubiquitous beta distribution, improving upon sub-Gaussian and sub-gamma bounds previously studied in this context.
Maciej Skorski
doaj +1 more source
Herd Behaviors in Financial Markets
We investigate the herd behavior of returns for the yen-dollar exchange rate in the Japanese financial market. It is obtained that the probability distribution $P(R)$ of returns $R$ satisfies the power-law behavior $P(R) \simeq R^{-\beta}$ with the ...
Choi, J. S. +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

